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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Permanent crash of estrogen?
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<blockquote data-quote="zancek0" data-source="post: 257243" data-attributes="member: 45189"><p>[USER=41815]@Nocalves[/USER]</p><p></p><p>Thank you for your informative reply!</p><p>Okay, new questions are here (when you'll have extra time to answer, haha):</p><p></p><p>2. So you didn't notice any difference between injections, pills and creams for progesterone in terms of symptoms? They all decrease E2? I ask that because some people seem to better react to certain forms and not others.</p><p></p><p>3. You tried MENT+E2 in this last experiment? Maybe you don't need E2 with MENT. It could compete with the more potent (due to longer half life) methylestradiol that MENT aromatizes into. That's just a thought, can't be sure.</p><p></p><p>Have you tried test propionate to test how you feel?</p><p>Also, since you're an experimentator - there's a member on this forum that also has long term aromasin damage and he reported that testosterone cream on abdomen (idk if he tried scrotum) raises his e2 the most.</p><p></p><p>4. There is a possibility that it's not only low E2 that's the issue but also high androgen activity due to high DHT levels (that's why I asked what your DHT levels are). This is especially relevant with low SHBG where there's potentially more free DHT floating around.</p><p>Nandrolone converts to less potent DHN instead of DHT, reducing androgen activity. However, it doesn't aromatize so you need to combine it with testosterone (some report increased aromatization when they combine the two). Ofc, it also has progestogenic activity (potentially competing with E2) so it's not perfect for guys like us who don't have enough E2. It is still very much worth experimenting with. I wonder how you would feel on it. You could try a protocol: 100mg test and 100mg nandrolone or something like that. Maybe add a small dose of injectable E2 if it would be necessary.</p><p>Or maybe oral E2. Have you tried E2 pills yet?</p><p></p><p>X. What about your thyroid function? There's much interaction between thyroid and E2 on the level of receptors. Addressing suboptimal thyroid could lead to sensitisation of estrogen receptors.</p><p>Insulin resistance also plays a role here. As well as chronic inflammation. They both seem to make estrogen receptors less receptive.</p><p>All this also affects aromatase activity. Elevated cortisol inhibits it in many cases.</p><p>Anyway, there's more factors at play that you might benefit from looking into.</p><p></p><p>Thanks again for your answers!</p></blockquote><p></p>
[QUOTE="zancek0, post: 257243, member: 45189"] [USER=41815]@Nocalves[/USER] Thank you for your informative reply! Okay, new questions are here (when you'll have extra time to answer, haha): 2. So you didn't notice any difference between injections, pills and creams for progesterone in terms of symptoms? They all decrease E2? I ask that because some people seem to better react to certain forms and not others. 3. You tried MENT+E2 in this last experiment? Maybe you don't need E2 with MENT. It could compete with the more potent (due to longer half life) methylestradiol that MENT aromatizes into. That's just a thought, can't be sure. Have you tried test propionate to test how you feel? Also, since you're an experimentator - there's a member on this forum that also has long term aromasin damage and he reported that testosterone cream on abdomen (idk if he tried scrotum) raises his e2 the most. 4. There is a possibility that it's not only low E2 that's the issue but also high androgen activity due to high DHT levels (that's why I asked what your DHT levels are). This is especially relevant with low SHBG where there's potentially more free DHT floating around. Nandrolone converts to less potent DHN instead of DHT, reducing androgen activity. However, it doesn't aromatize so you need to combine it with testosterone (some report increased aromatization when they combine the two). Ofc, it also has progestogenic activity (potentially competing with E2) so it's not perfect for guys like us who don't have enough E2. It is still very much worth experimenting with. I wonder how you would feel on it. You could try a protocol: 100mg test and 100mg nandrolone or something like that. Maybe add a small dose of injectable E2 if it would be necessary. Or maybe oral E2. Have you tried E2 pills yet? X. What about your thyroid function? There's much interaction between thyroid and E2 on the level of receptors. Addressing suboptimal thyroid could lead to sensitisation of estrogen receptors. Insulin resistance also plays a role here. As well as chronic inflammation. They both seem to make estrogen receptors less receptive. All this also affects aromatase activity. Elevated cortisol inhibits it in many cases. Anyway, there's more factors at play that you might benefit from looking into. Thanks again for your answers! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Permanent crash of estrogen?
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