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lets try and keep this factual guys and not personal. If someone disagrees with another's supposition, simply state that you disagree and present the facts as to why.

There is no need to belittle or ridicule.

I tend to agree with the content in Madman's posts. I have been researching ED and it’s multitude of causes for many years now. PDE5i show promising effects with regard to the reduction of oxidative stress in our peripheral vascular system. In some instances even being possibly capable of reversing some of the damage to smooth muscle and the endothelial cells producing NO.

Excessive oxidative stress is one of the most significant causes of deterioration in the vascular tissues as we age. This is particularly evident in those with diabetes. The penis is especially vulnerable to this owing to its very high dependence on the health and function of its smooth muscle content and the sufficient availability of NO. It has been suggested that only a 15% loss of the smooth muscle content in the erectile tissues will cause erectile difficulties and this can begin as early as the third decade of life for some of us.