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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Penile fibrosis after long time without morning erections?
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<blockquote data-quote="Simbarn" data-source="post: 230050" data-attributes="member: 44021"><p>Ok, you have provided a little more insight into your issue.</p><p>You did use HCG in your restart attempts. The more accurate information you provide does help a great deal for anyone here on this forum trying to help you.</p><p>The tapers are very important when doing a restart. You mentioned earlier you only took Clomid for 2-3 weeks per time, which does not leave any time for a reasonable taper off.</p><p></p><p>I am a little confused at this point. Did your total testosterone, plus your LH and FSH recover to an acceptable level after discontinuing Clomid and stay that way?</p><p>From what you have just said, some of the Endocrinologists that you saw determined that your hormones were recovered and given that, you did not require hormone replacement?</p><p>You have also said that it was not just borderline ok, but quite above this, correct?</p><p>Your main complaint was sexual function, not low hormone levels, correct?</p><p></p><p>So it appears to me you recovered your natural hormone function quite well, but kept doing cycles of Clomid to try and reinstate sexual function?</p><p>Clomid only works to recover your production of gonadotropins, if it does this, it has done its job. No point in continuing it to try and fix sexual dysfunction, when part of this dysfunction maybe caused by the Clomid itself.</p><p></p><p>Clomid will interfere with sexual function in many men. It will continue to do this for some time afterward also. I talked about this earlier on.</p><p></p><p>If your hormone levels did return to normal, do you really think you should be on TRT? Your body may need some time to firstly clear the residual Clomid out of your body and then many months to find homeostasis again.</p><p>Sexual function may take a long time to return, especially after all these episodes on Clomid and the initial trauma caused by AAS use.</p><p></p><p>How long was the longest period you left your body alone to recover after stopping all these drugs? In earlier posts of yours you mention only one month, later ones a couple of months.</p><p></p><p>“<em>I already accepted life on trt and if I fix the erectile function I won't quit.</em>”</p><p>If your endogenous hormones were at acceptable levels, why would your doctor put you onto TRT?</p><p>If your Testosterone was at a good level before you started TRT, undertaking T replacement will not fix your erectile dysfunction, in fact quite the opposite. This is well understood.</p><p></p><p>The unfortunate thing about all of this is that you have shut all your hormones down again after the apparent full recovery. This is not good. I am not including erectile function here in that recovery as this can be a very separate issue.</p><p></p><p>It is the culmination of many years of learning about ED and reading many papers that has given me all the information I need to understand that high T is not good. It is not one specific paper that has determined this in the human.</p><p>Some have discussed tissue changes in the rat model. Many discuss how hormones alter neurotransmission, the autonomic nervous system and sympathetic activity in the penis.</p><p>It is very difficult to do any trials on human subjects as we cannot subject them to high levels of androgens and then sacrifice their penises for examination at a histological level! Even getting subjects willing to do a biopsy would be extremely difficult.</p><p>Hence why much of this is done with rabbits and rats.</p><p>If you are interested you should start researching yourself, especially if you are determined to stay on TRT.</p><p></p><p>If you had an enlarged prostate, which I doubt at 33, you would most likely be experiencing changes in your ability to urinate. From what I understand ED and PE are separate issues. It is more the drugs used to treat PE that can contribute to ED.</p><p>Research has shown a connection with an increase in adrenergic receptor expression/activity in the tissues of both organs however, as men age. This does not mean one causes the other.</p><p></p><p>As you may be pre-diabetic, meaning you were becoming insulin resistant, this in itself can cause many issues in the body. Diabetes 2 is a high risk factor for erectile dysfunction. I do not think managing insulin resistance with high levels of Testosterone is appropriate.</p><p></p><p>What do you think is possibly wrong with your diet and lifestyle that has caused your insulin resistance?</p></blockquote><p></p>
[QUOTE="Simbarn, post: 230050, member: 44021"] Ok, you have provided a little more insight into your issue. You did use HCG in your restart attempts. The more accurate information you provide does help a great deal for anyone here on this forum trying to help you. The tapers are very important when doing a restart. You mentioned earlier you only took Clomid for 2-3 weeks per time, which does not leave any time for a reasonable taper off. I am a little confused at this point. Did your total testosterone, plus your LH and FSH recover to an acceptable level after discontinuing Clomid and stay that way? From what you have just said, some of the Endocrinologists that you saw determined that your hormones were recovered and given that, you did not require hormone replacement? You have also said that it was not just borderline ok, but quite above this, correct? Your main complaint was sexual function, not low hormone levels, correct? So it appears to me you recovered your natural hormone function quite well, but kept doing cycles of Clomid to try and reinstate sexual function? Clomid only works to recover your production of gonadotropins, if it does this, it has done its job. No point in continuing it to try and fix sexual dysfunction, when part of this dysfunction maybe caused by the Clomid itself. Clomid will interfere with sexual function in many men. It will continue to do this for some time afterward also. I talked about this earlier on. If your hormone levels did return to normal, do you really think you should be on TRT? Your body may need some time to firstly clear the residual Clomid out of your body and then many months to find homeostasis again. Sexual function may take a long time to return, especially after all these episodes on Clomid and the initial trauma caused by AAS use. How long was the longest period you left your body alone to recover after stopping all these drugs? In earlier posts of yours you mention only one month, later ones a couple of months. “[I]I already accepted life on trt and if I fix the erectile function I won't quit.[/I]” If your endogenous hormones were at acceptable levels, why would your doctor put you onto TRT? If your Testosterone was at a good level before you started TRT, undertaking T replacement will not fix your erectile dysfunction, in fact quite the opposite. This is well understood. The unfortunate thing about all of this is that you have shut all your hormones down again after the apparent full recovery. This is not good. I am not including erectile function here in that recovery as this can be a very separate issue. It is the culmination of many years of learning about ED and reading many papers that has given me all the information I need to understand that high T is not good. It is not one specific paper that has determined this in the human. Some have discussed tissue changes in the rat model. Many discuss how hormones alter neurotransmission, the autonomic nervous system and sympathetic activity in the penis. It is very difficult to do any trials on human subjects as we cannot subject them to high levels of androgens and then sacrifice their penises for examination at a histological level! Even getting subjects willing to do a biopsy would be extremely difficult. Hence why much of this is done with rabbits and rats. If you are interested you should start researching yourself, especially if you are determined to stay on TRT. If you had an enlarged prostate, which I doubt at 33, you would most likely be experiencing changes in your ability to urinate. From what I understand ED and PE are separate issues. It is more the drugs used to treat PE that can contribute to ED. Research has shown a connection with an increase in adrenergic receptor expression/activity in the tissues of both organs however, as men age. This does not mean one causes the other. As you may be pre-diabetic, meaning you were becoming insulin resistant, this in itself can cause many issues in the body. Diabetes 2 is a high risk factor for erectile dysfunction. I do not think managing insulin resistance with high levels of Testosterone is appropriate. What do you think is possibly wrong with your diet and lifestyle that has caused your insulin resistance? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
When Testosterone Is Not Enough
Penile fibrosis after long time without morning erections?
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