ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Peak & Trough levels for TRT
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="Cataceous" data-source="post: 193452" data-attributes="member: 38109"><p>Maybe you're aware that "half-life" is a measurement of how quickly a drug is used up in the body—how long it takes for half of the drug to be used up. The model it's based on assumes the rate of drug use is always directly proportional to the amount present. This makes the half-life constant, no matter how much drug is present. It's not a perfect model, but it is reasonably consistent with measured data.</p><p></p><p>The reason for my comment is that there's research and anecdotal data showing the half-lives for testosterone cypionate and testosterone enanthate to be more like five days. The question is, why do XYOSTED and Delatestryl have apparent half-lives that are twice as long? The clinical trial for XYOSTED I linked to above came up with a half-life of 239 hours, comparable to a calculation based on the Delatestryl data. A possible contributing factor is that unlike XYOSTED and Delatestryl, most testosterone formulations contain benzyl alcohol as a preservative, which is known to speed absorption, and therefore reduce the half-lives. I don't know if this is the whole story.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 193452, member: 38109"] Maybe you're aware that "half-life" is a measurement of how quickly a drug is used up in the body—how long it takes for half of the drug to be used up. The model it's based on assumes the rate of drug use is always directly proportional to the amount present. This makes the half-life constant, no matter how much drug is present. It's not a perfect model, but it is reasonably consistent with measured data. The reason for my comment is that there's research and anecdotal data showing the half-lives for testosterone cypionate and testosterone enanthate to be more like five days. The question is, why do XYOSTED and Delatestryl have apparent half-lives that are twice as long? The clinical trial for XYOSTED I linked to above came up with a half-life of 239 hours, comparable to a calculation based on the Delatestryl data. A possible contributing factor is that unlike XYOSTED and Delatestryl, most testosterone formulations contain benzyl alcohol as a preservative, which is known to speed absorption, and therefore reduce the half-lives. I don't know if this is the whole story. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Peak & Trough levels for TRT
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top