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Osteoarthritis and adding nandrolone to TRT
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<blockquote data-quote="BigTex" data-source="post: 220995" data-attributes="member: 43589"><p>Thanks! Done the HGH already , hopefully it is working, but I found IGF-1 Lr3 is much better, along with BPC 157, EGF and MGF. I used that combination of my quad surgery. I did micro injections around the repair for 6 weeks. At 55 years old my surgeon said I was the poster child for recovery from quad reattachment surgery. He has never seen any of his pro athletes return so quickly. He was aware of what I was doing but said he could not condone this type of therapy but know athletes do what they have to do. I did also have PRP done after surgery. It was still very experimental at that point.</p><p></p><p></p><p>OK, I found a little research on why sports medicine doctors claim it is best to continue working out with osteoarthritis. My doctor is a shoulder specialist and would absolutely not be my doctor had I suspected he didn't have a clue what he was talking about. I have probably more knowledge in the area (other that the surgical side) than he does. Its my profession too.</p><p></p><p>Latham, Nancy, and Chiung-ju Liu. “<strong>Strength training in older adults: the benefits for osteoarthritis.</strong>” <em>Clinics in geriatric medicine</em> vol. 26,3 (2010): 445-59. doi:10.1016/j.cger.2010.03.006</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/" target="_blank">Strength training in older adults: The benefits for osteoarthritis</a></p><p></p><p><strong>Synopsis</strong></p><p></p><p>The aim of this review was to summarize the findings of randomized controlled trials (RCTs) of progressive resistance strength training (PRT) by older people with osteoarthritis (OA). When data from 8 RCTs were synthesized using meta-analysis, a significant benefit from PRT was found on lower extremity extensor strength (standardized mean difference (SMD) 0.33, 95% confidence interval (CI) 0.12, 0.54), function (SMD 0.33, 95% CI 0.18) and pain reduction −0.35 (95% CI −0.52, −0.18). Across all three outcomes, the estimated effect size was moderate, which contrasted with trials of PRT in non-OA specific groups of older adults where a large effect was found on strength, but a small effect on function. This suggests that strength training has particularly strong functional benefits for older adults with OA. Older adults with osteoarthritis will benefit from a strength training program that provides progressive overload to maintain intensity throughout the exercise program. Clinicians should encourage participation in exercise training programs, even in the oldest old with OA.</p><p></p><p>Muscle weakness, particularly of the knee extensors, is common in people with OA<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R7" target="_blank">7</a>, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R20" target="_blank">20</a> and has been consistently shown to be associated with an increased risk of functional limitations and disability.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R20" target="_blank">20</a>, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R21" target="_blank">21</a> The Bristol Knee OA study found lower limb strength to be a stronger predictor of functional limitations than radiographic severity or knee pain.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R21" target="_blank">21</a></p><p></p><p>The nature of the cause –effect relationship between muscle weakness and OA is complex, and has been widely debated. While strength probably declines in people with OA as a secondary result of reduced activity, there is also evidence that muscle weakness directly contributes to the development and progression of OA.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R20" target="_blank">20</a> Muscle strength appears to have a protective effect against the disability associated with progressing OA. In a longitudinal study that monitored a cohort of women with for 6 years who had no functional limitations at baseline, knee extensor strength was protective against the development of functional limitations associated with OA.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R22" target="_blank">22</a></p><p></p><p><strong>There are also a large number of randomized controlled clinical trials (RCTs) that support the benefits of exercise in general, and strength training in particular, in people with OA. Recent systematic reviews and guidelines have summarized the evidence for the effectiveness of strength training in people with osteoarthritis, and have found that strength training has a significant benefit in improving strength and function and in reducing pain.<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R9" target="_blank">9</a>–<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R11" target="_blank">11</a> [/b} However, these reviews have also found that the reductions in pain and improvements in function are modest.</strong></p><p><strong></strong></p><p><strong><strong>Summary and Recommendations</strong></strong></p><p><strong></strong></p><p><strong>Older adults with osteoarthritis will benefit from a strength training program that provides progressive overload to maintain intensity throughout the exercise program. Significant improvements in strength and function and pain reduction were seen when the data from 8 RCTs were synthesized, and there was a moderate effect size for all three outcomes.</strong></p><p><strong></strong></p><p><strong>Clinicians should encourage participation in exercise training programs, even in the oldest old with OA. There is no evidence that there is significantly decreased efficacy or increased risk of adverse events when older adults with OA participate in exercise programs compared to younger adults. People with OA should be reassured that it is unlikely to exacerbate their pain if performed using the appropriate methods and at the appropriate dose. In fact, the evidence suggests that it will decrease pain in most older people.</strong></p><p><strong></strong></p><p><strong>Ettinger WH Jr, Burns R, Messier SP, Applegate W, Rejeski WJ, Morgan T, Shumaker S, Berry MJ, O'Toole M, Monu J, Craven T. <strong>A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis</strong>. The Fitness Arthritis and Seniors Trial (FAST). JAMA. 1997 Jan 1;277(1):25-31. PMID: 8980206.</strong></p><p><strong><h2>Abstract</h2><p><strong>Objective: </strong>To determine the effects of structured exercise programs on self-reported disability in older adults with knee osteoarthritis.</strong></p><p><strong></strong></p><p><strong><strong>Setting and design: </strong>A randomized, single-blind clinical trial lasting 18 months conducted at 2 academic medical centers.</strong></p><p><strong></strong></p><p><strong><strong>Participants: </strong>A total of 439 community-dwelling adults, aged 60 years or older, with radiographically evident knee osteoarthritis, pain, and self-reported physical disability.</strong></p><p><strong></strong></p><p><strong><strong>Interventions: </strong>An aerobic exercise program, a resistance exercise program, and a health education program.</strong></p><p><strong></strong></p><p><strong><strong>Main outcome measures: </strong>The primary outcome was self-reported disability score (range, 1-5). The secondary outcomes were knee pain score (range, 1-6), performance measures of physical function, x-ray score, aerobic capacity, and knee muscle strength.</strong></p><p><strong></strong></p><p><strong><strong>Results: </strong>A total of 365 (83%) participants completed the trial. Overall compliance with the exercise prescription was 68% in the aerobic training group and 70% in the resistance training group. Postrandomization, participants in the aerobic exercise group had a 10% lower adjusted mean (+/- SE) score on the physical disability questionnaire (1.71 +/- 0.03 vs 1.90 +/- 0.04 units; P<.001), a 12% lower score on the knee pain questionnaire (2.1 +/- 0.05 vs 2.4 +/- 0.05 units; P=.001), and performed better (mean [+/- SE]) on the 6-minute walk test (1507 +/- 16 vs 1349 +/- 16 ft; P<.001), mean (+/-SE) time to climb and descend stairs (12.7 +/- 0.4 vs 13.9 +/- 0.4 seconds; P=.05), time to lift and carry 10 pounds (9.1 +/- 0.2 vs 10.0 +/- 0.1 seconds; P<.001), and mean (+/-SE) time to get in and out of a car (8.7 +/- 0.3 vs 10.6 +/- 0.3 seconds; P<.001) than the health education group. The resistance exercise group had an 8% lower score on the physical disability questionnaire (1.74 +/- 0.04 vs 1.90 +/- 0.03 units; P=.003), 8% lower pain score (2.2 +/- 0.06 vs 2.4 +/- 0.05 units; P=.02), greater distance on the 6-minute walk (1406 +/- 17 vs 1349 +/- 16 ft; P=.02), faster times on the lifting and carrying task (9.3 +/- 0.1 vs 10.0 +/- 0.16 seconds; P=.001), and the car task (9.0 +/- 0.3 vs 10.6 +/- 0.3 seconds; P=.003) than the health education group. There were no differences in x-ray scores between either exercise group and the health education group.</strong></p><p><strong></strong></p><p><strong><strong>Conclusions: </strong>Older disabled persons with osteoarthritis of the knee had modest improvements in measures of disability, physical performance, and pain from participating in either an aerobic or a resistance exercise program. These data suggest that exercise should be prescribed as part of the treatment for knee osteoarthritis.</strong></p><p><strong></strong></p><p><strong>Can you lift weights after joint replacement? Patients are often most surprised to learn that <strong>they are not only permitted to lift weights but are encouraged to lift weights after receiving a joint replacement</strong>. In fact, lifting weights is the best thing a patient can do for the prolonged life of their artificial joint. Weight training strengthens muscles and increases bone density, all while being relatively easy on the joints. Like I mentioned powerlifter Gary Frank had double knee replacement surgery after playing in the NGF. 5-6 after his surgery he set the all time heavies total and squat lifting in the superheavyweight division. It took him a few years to regain his ROM in the knee and had difficulty at first breaking parallel on the squat.</strong></p><p><strong></strong></p><p><strong>Symptomatic glenohumeral arthritis (GHA) among high-level bodybuilders and powerlifters is relatively common. However, it is suspected that it is more likely related to genetic factors, age and or traumatic injury (ie. football). Joints, connective tissue and vertebral disk slowly degenerate with age. As a matter of fact, joint arthritis is so common as we age it is estimated that over 60% of people over 50 have some form of arthritis. So is more prevalent in these two sports or perhaps is it invadable as we age. Chuck Norris also had hip replacement surgery. Certainly not a bodybuilder or powerlifter. One of our ex-professors retired after getting hip replacement surgery. She was big into aerobics exercise.</strong></p><p><strong></strong></p><p><strong>Uribe J, Luis Vargas John Z. <strong>Minimum 2 Years Outcomes of Powerlifters and Bodybuilders with advanced Glenohumeral arthritis, managed with Stemless aspherical humeral head resurfacing and inlay glenoid.</strong> <em>Orthopaedic Journal of Sports Medicine</em>. July 2020. doi:<a href="https://doi.org/10.1177/2325967120S00417" target="_blank">10.1177/2325967120S00417</a></strong></p><p><strong></strong></p><p><strong>Stemless aspherical humeral head resurfacing combined with inlay glenoid replacement provides substantial pain relief and functional improvement and is a promising option for the management of symptomatic osteoarthritis in this challenging patient population. The procedure allows for a return to activities without restrictions and leaves multiple arthroplasty options if revision becomes necessary.</strong></p></blockquote><p></p>
[QUOTE="BigTex, post: 220995, member: 43589"] Thanks! Done the HGH already , hopefully it is working, but I found IGF-1 Lr3 is much better, along with BPC 157, EGF and MGF. I used that combination of my quad surgery. I did micro injections around the repair for 6 weeks. At 55 years old my surgeon said I was the poster child for recovery from quad reattachment surgery. He has never seen any of his pro athletes return so quickly. He was aware of what I was doing but said he could not condone this type of therapy but know athletes do what they have to do. I did also have PRP done after surgery. It was still very experimental at that point. OK, I found a little research on why sports medicine doctors claim it is best to continue working out with osteoarthritis. My doctor is a shoulder specialist and would absolutely not be my doctor had I suspected he didn't have a clue what he was talking about. I have probably more knowledge in the area (other that the surgical side) than he does. Its my profession too. Latham, Nancy, and Chiung-ju Liu. “[B]Strength training in older adults: the benefits for osteoarthritis.[/B]” [I]Clinics in geriatric medicine[/I] vol. 26,3 (2010): 445-59. doi:10.1016/j.cger.2010.03.006 [URL="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/"]Strength training in older adults: The benefits for osteoarthritis[/URL] [b]Synopsis[/b] The aim of this review was to summarize the findings of randomized controlled trials (RCTs) of progressive resistance strength training (PRT) by older people with osteoarthritis (OA). When data from 8 RCTs were synthesized using meta-analysis, a significant benefit from PRT was found on lower extremity extensor strength (standardized mean difference (SMD) 0.33, 95% confidence interval (CI) 0.12, 0.54), function (SMD 0.33, 95% CI 0.18) and pain reduction −0.35 (95% CI −0.52, −0.18). Across all three outcomes, the estimated effect size was moderate, which contrasted with trials of PRT in non-OA specific groups of older adults where a large effect was found on strength, but a small effect on function. This suggests that strength training has particularly strong functional benefits for older adults with OA. Older adults with osteoarthritis will benefit from a strength training program that provides progressive overload to maintain intensity throughout the exercise program. Clinicians should encourage participation in exercise training programs, even in the oldest old with OA. Muscle weakness, particularly of the knee extensors, is common in people with OA[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R7']7[/URL], [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R20']20[/URL] and has been consistently shown to be associated with an increased risk of functional limitations and disability.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R20']20[/URL], [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R21']21[/URL] The Bristol Knee OA study found lower limb strength to be a stronger predictor of functional limitations than radiographic severity or knee pain.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R21']21[/URL] The nature of the cause –effect relationship between muscle weakness and OA is complex, and has been widely debated. While strength probably declines in people with OA as a secondary result of reduced activity, there is also evidence that muscle weakness directly contributes to the development and progression of OA.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R20']20[/URL] Muscle strength appears to have a protective effect against the disability associated with progressing OA. In a longitudinal study that monitored a cohort of women with for 6 years who had no functional limitations at baseline, knee extensor strength was protective against the development of functional limitations associated with OA.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R22']22[/URL] [b]There are also a large number of randomized controlled clinical trials (RCTs) that support the benefits of exercise in general, and strength training in particular, in people with OA. Recent systematic reviews and guidelines have summarized the evidence for the effectiveness of strength training in people with osteoarthritis, and have found that strength training has a significant benefit in improving strength and function and in reducing pain.[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R9']9[/URL]–[URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606891/#R11']11[/URL] [/b} However, these reviews have also found that the reductions in pain and improvements in function are modest. [B]Summary and Recommendations[/B] Older adults with osteoarthritis will benefit from a strength training program that provides progressive overload to maintain intensity throughout the exercise program. Significant improvements in strength and function and pain reduction were seen when the data from 8 RCTs were synthesized, and there was a moderate effect size for all three outcomes. Clinicians should encourage participation in exercise training programs, even in the oldest old with OA. There is no evidence that there is significantly decreased efficacy or increased risk of adverse events when older adults with OA participate in exercise programs compared to younger adults. People with OA should be reassured that it is unlikely to exacerbate their pain if performed using the appropriate methods and at the appropriate dose. In fact, the evidence suggests that it will decrease pain in most older people. Ettinger WH Jr, Burns R, Messier SP, Applegate W, Rejeski WJ, Morgan T, Shumaker S, Berry MJ, O'Toole M, Monu J, Craven T. [B]A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis[/B]. The Fitness Arthritis and Seniors Trial (FAST). JAMA. 1997 Jan 1;277(1):25-31. PMID: 8980206. [HEADING=1]Abstract[/HEADING] [B]Objective: [/B]To determine the effects of structured exercise programs on self-reported disability in older adults with knee osteoarthritis. [B]Setting and design: [/B]A randomized, single-blind clinical trial lasting 18 months conducted at 2 academic medical centers. [B]Participants: [/B]A total of 439 community-dwelling adults, aged 60 years or older, with radiographically evident knee osteoarthritis, pain, and self-reported physical disability. [B]Interventions: [/B]An aerobic exercise program, a resistance exercise program, and a health education program. [B]Main outcome measures: [/B]The primary outcome was self-reported disability score (range, 1-5). The secondary outcomes were knee pain score (range, 1-6), performance measures of physical function, x-ray score, aerobic capacity, and knee muscle strength. [B]Results: [/B]A total of 365 (83%) participants completed the trial. Overall compliance with the exercise prescription was 68% in the aerobic training group and 70% in the resistance training group. Postrandomization, participants in the aerobic exercise group had a 10% lower adjusted mean (+/- SE) score on the physical disability questionnaire (1.71 +/- 0.03 vs 1.90 +/- 0.04 units; P<.001), a 12% lower score on the knee pain questionnaire (2.1 +/- 0.05 vs 2.4 +/- 0.05 units; P=.001), and performed better (mean [+/- SE]) on the 6-minute walk test (1507 +/- 16 vs 1349 +/- 16 ft; P<.001), mean (+/-SE) time to climb and descend stairs (12.7 +/- 0.4 vs 13.9 +/- 0.4 seconds; P=.05), time to lift and carry 10 pounds (9.1 +/- 0.2 vs 10.0 +/- 0.1 seconds; P<.001), and mean (+/-SE) time to get in and out of a car (8.7 +/- 0.3 vs 10.6 +/- 0.3 seconds; P<.001) than the health education group. The resistance exercise group had an 8% lower score on the physical disability questionnaire (1.74 +/- 0.04 vs 1.90 +/- 0.03 units; P=.003), 8% lower pain score (2.2 +/- 0.06 vs 2.4 +/- 0.05 units; P=.02), greater distance on the 6-minute walk (1406 +/- 17 vs 1349 +/- 16 ft; P=.02), faster times on the lifting and carrying task (9.3 +/- 0.1 vs 10.0 +/- 0.16 seconds; P=.001), and the car task (9.0 +/- 0.3 vs 10.6 +/- 0.3 seconds; P=.003) than the health education group. There were no differences in x-ray scores between either exercise group and the health education group. [B]Conclusions: [/B]Older disabled persons with osteoarthritis of the knee had modest improvements in measures of disability, physical performance, and pain from participating in either an aerobic or a resistance exercise program. These data suggest that exercise should be prescribed as part of the treatment for knee osteoarthritis. Can you lift weights after joint replacement? Patients are often most surprised to learn that [B]they are not only permitted to lift weights but are encouraged to lift weights after receiving a joint replacement[/B]. In fact, lifting weights is the best thing a patient can do for the prolonged life of their artificial joint. Weight training strengthens muscles and increases bone density, all while being relatively easy on the joints. Like I mentioned powerlifter Gary Frank had double knee replacement surgery after playing in the NGF. 5-6 after his surgery he set the all time heavies total and squat lifting in the superheavyweight division. It took him a few years to regain his ROM in the knee and had difficulty at first breaking parallel on the squat. Symptomatic glenohumeral arthritis (GHA) among high-level bodybuilders and powerlifters is relatively common. However, it is suspected that it is more likely related to genetic factors, age and or traumatic injury (ie. football). Joints, connective tissue and vertebral disk slowly degenerate with age. As a matter of fact, joint arthritis is so common as we age it is estimated that over 60% of people over 50 have some form of arthritis. So is more prevalent in these two sports or perhaps is it invadable as we age. Chuck Norris also had hip replacement surgery. Certainly not a bodybuilder or powerlifter. One of our ex-professors retired after getting hip replacement surgery. She was big into aerobics exercise. Uribe J, Luis Vargas John Z. [b]Minimum 2 Years Outcomes of Powerlifters and Bodybuilders with advanced Glenohumeral arthritis, managed with Stemless aspherical humeral head resurfacing and inlay glenoid.[/b] [I]Orthopaedic Journal of Sports Medicine[/I]. July 2020. doi:[URL='https://doi.org/10.1177/2325967120S00417']10.1177/2325967120S00417[/URL] Stemless aspherical humeral head resurfacing combined with inlay glenoid replacement provides substantial pain relief and functional improvement and is a promising option for the management of symptomatic osteoarthritis in this challenging patient population. The procedure allows for a return to activities without restrictions and leaves multiple arthroplasty options if revision becomes necessary.[/b] [/QUOTE]
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