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Dr Saya... Just discovered that LabCorp has changed the methodology of E2 (Sensitive)Test #140244 from RIA to LC/MS-MS. According to some posts at All Things Male their results are coming in contrary to what we have seen in the past. Utilizing their current methodology the readings are coming in HIGHER than their standard E2 test, whereas most had just the opposite levels before this change. Several had similar readings to mine...standard test in mid to high 20's, sensitive test in high 30's to low 40's...with range of 8-35. Not sure what to trust at this point...could definitely impact HRT protocol for many...self included! Appreciate any and all of your input....Roy

[QUOTE="olddawg, post: 32380, member: 12671"] Dr Saya... Just discovered that LabCorp has changed the methodology of E2 (Sensitive)Test #140244 from RIA to LC/MS-MS. According to some posts at All Things Male their results are coming in contrary to what we have seen in the past. Utilizing their current methodology the readings are coming in HIGHER than their standard E2 test, whereas most had just the opposite levels before this change. Several had similar readings to mine...standard test in mid to high 20's, sensitive test in high 30's to low 40's...with range of 8-35. Not sure what to trust at this point...could definitely impact HRT protocol for many...self included! Appreciate any and all of your input....Roy [/QUOTE]