The Optilume BPH Catheter System is a non-surgical treatment for benign prostatic hyperplasia (BPH) in aging men. It involves balloon dilation and localized transfer of paclitaxel to maintain patency. The procedure is performed using rigid cystoscopy in an office setting, without general anesthesia. Prospective data show promising functional and sexual outcomes. The article provides information about Optilume BPH, historical studies, and the deployment technique.
Key Takeaways:
The Optilume BPH catheter system is effective for treating various prostate glands without general anesthesia.
It bridges the gap between conservative medical therapy and more invasive surgical procedures.
The technology is deployable using standard cystoscopes in a urology office.
Promising results from prospective studies and randomized controlled trials support its use.
A standardized technique can lead to successful outcomes and be easily reproducible.
Practitioners are advised to take time, gain experience, and confidence, and refine their technique with the new technology.
Figure 3. Fluoroscopic images during Optilume procedure. A) A wire has been placed through the urethral stricture and into the bladder, the flexible cystoscope has been advanced just distal to stricture and the Optilume balloon begins to be filled with contrast. Note radio-opaque markers on proximal and distal balloon seen over the guidewire. B) The partially-inflated Optilume balloon shows a narrowing, approximately 1.5cm long,
indicating proper placement proximally and distally on the bulbar urethral stricture. C) Optilume is fully inflated over guidewire and alongside flexible scope. Inflation is complete to recommended pressure. Inflated balloon spans area of previously seen stricture and no "waisting" can be seen.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
⚠️ Medical Disclaimer
This tool provides predictions based on statistical models and should NOT replace professional medical advice.
Always consult with your healthcare provider before making any changes to your TRT protocol.
ℹ️ Input Parameters
Normal range: 300-1000 ng/dL
Predicted Hormone Levels
Enter your total testosterone value to see predictions
Results will appear here after calculation
Understanding Your Hormones
Estradiol (E2)
A form of estrogen produced from testosterone. Important for bone health, mood, and libido.
Too high can cause side effects; too low can affect well-being.
DHT
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth,
prostate health, and masculinization effects.
Free Testosterone
The biologically active form of testosterone not bound to proteins.
Directly available for cellular uptake and biological effects.
Scientific Reference
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
