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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Opinion on Test/Adex adjustment
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<blockquote data-quote="CoastWatcher" data-source="post: 77153" data-attributes="member: 2624"><p>Men are terrified of estradiol. They regard it as a noxious waste product that must be eliminated from their body. In reality, e2 is a necessary hormone for sexual function, skeletal and cognitive health, and emotional stability. As uncomfortable as elevated estradiol may be, the misery associated with crashed estradiol is a terrible experience. There is no validated research that says 20-30 is the ideal range for estradiol in men. That's a reasonable assumption, but it may not apply to you. </p><p></p><p>Many feel well with estradiol levels in the mid to upper 30s, I do. We have members who are at their best if their e2 climbs to the low 40s. Symptoms guide this decision...symptoms and the proper estradiol test. Quite bluntly, you really don't know where your estradiol sits because you don't use the proper assay. It has nothing to do with ranges, as you write, and everything to do with the underlying lab test. Men require the sensitive, sometimes known as ultra sensitive, test to measure estradiol. This test utilizes liquid chromatography, dual mass spectrometry analysis to detect the lower levels of estradiol typically found in men. The ECLIA method you rely on is fine for women, unreliable for men.</p></blockquote><p></p>
[QUOTE="CoastWatcher, post: 77153, member: 2624"] Men are terrified of estradiol. They regard it as a noxious waste product that must be eliminated from their body. In reality, e2 is a necessary hormone for sexual function, skeletal and cognitive health, and emotional stability. As uncomfortable as elevated estradiol may be, the misery associated with crashed estradiol is a terrible experience. There is no validated research that says 20-30 is the ideal range for estradiol in men. That's a reasonable assumption, but it may not apply to you. Many feel well with estradiol levels in the mid to upper 30s, I do. We have members who are at their best if their e2 climbs to the low 40s. Symptoms guide this decision...symptoms and the proper estradiol test. Quite bluntly, you really don't know where your estradiol sits because you don't use the proper assay. It has nothing to do with ranges, as you write, and everything to do with the underlying lab test. Men require the sensitive, sometimes known as ultra sensitive, test to measure estradiol. This test utilizes liquid chromatography, dual mass spectrometry analysis to detect the lower levels of estradiol typically found in men. The ECLIA method you rely on is fine for women, unreliable for men. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Opinion on Test/Adex adjustment
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