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I guess the only symptom is my hair seems to be falling out quicker. I still don't have much of a libido even though I've been on TRT now for a few years and I've watched it come up from the low 200's to now around 800. The TRT has definitely had an impact on my energy levels. I apply the cream once a day per Rx. I guess I could say currently my only symptoms due to DHT raising is my hair falling out more so. I'm trying homeopathic remedies for my hair such as rosemary and minoxidil cream 5%. This combination seems to help a little. I guess my only worry about the DHT is how high it can get and where it will stop if it does stop. Every lab draw it seems to continue to go up.