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Mental Health
On demand neuroactive nasal spray for social anxiety disorders
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<blockquote data-quote="madman" data-source="post: 277910" data-attributes="member: 13851"><p><strong>Fasedienol (PH94B) Nasal Spray is a safe fast-acting and odourless neuroactive steroid</strong></p><p></p><p></p><p>[URL unfurl="true"]https://www.vistagen.com/pipeline/PH94B/overview[/URL]</p><p></p><p><strong>[ATTACH=full]42574[/ATTACH]</strong></p><h2>Fasedienol (PH94B) Nasal Spray for Social Anxiety Disorder</h2><p><em><strong>Vistagen’s fasedienol (PH94B) is a first-in-class, rapid-onset investigational neuroactive pherine nasal spray in Phase 3 clinical development for acute treatment of anxiety in adults with social anxiety disorder (SAD).</strong> Designed for intranasal administration in low microgram doses, the proposed novel mechanism of action (MOA) of fasedienol is fundamentally differentiated from all current anti-anxiety medications, including all antidepressants approved by the U.S. Food and Drug Administration (FDA) for the treatment of SAD, as well as all benzodiazepines and beta blockers prescribed for SAD on an off-label basis.</em></p><p><em></em></p><p><em><strong>When administered intranasally, fasedienol activates receptors of peripheral nasal chemosensory neurons connected to subsets of neurons in the olfactory bulbs that, in turn, connect to neurons in the limbic amygdala involved in the pathophysiology of SAD and potentially other anxiety and mood disorders. Fasedienol is pharmacologically active without requiring apparent systemic absorption and distribution of the compound to the brain to achieve its rapid-onset and short duration of anxiolytic effects.</strong></em></p><p></p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.vistagen.com/news/videos[/URL]</p><p></p><p><strong>[ATTACH=full]42570[/ATTACH]</strong></p><p><strong>[ATTACH=full]42571[/ATTACH]</strong></p><p><strong>[ATTACH=full]42572[/ATTACH]</strong></p><p><strong>[ATTACH=full]42573[/ATTACH]</strong></p></blockquote><p></p>
[QUOTE="madman, post: 277910, member: 13851"] [B]Fasedienol (PH94B) Nasal Spray is a safe fast-acting and odourless neuroactive steroid[/B] [URL unfurl="true"]https://www.vistagen.com/pipeline/PH94B/overview[/URL] [B][ATTACH type="full" alt="1711377983388.png"]42574[/ATTACH][/B] [HEADING=1]Fasedienol (PH94B) Nasal Spray for Social Anxiety Disorder[/HEADING] [I][B]Vistagen’s fasedienol (PH94B) is a first-in-class, rapid-onset investigational neuroactive pherine nasal spray in Phase 3 clinical development for acute treatment of anxiety in adults with social anxiety disorder (SAD).[/B] Designed for intranasal administration in low microgram doses, the proposed novel mechanism of action (MOA) of fasedienol is fundamentally differentiated from all current anti-anxiety medications, including all antidepressants approved by the U.S. Food and Drug Administration (FDA) for the treatment of SAD, as well as all benzodiazepines and beta blockers prescribed for SAD on an off-label basis. [B]When administered intranasally, fasedienol activates receptors of peripheral nasal chemosensory neurons connected to subsets of neurons in the olfactory bulbs that, in turn, connect to neurons in the limbic amygdala involved in the pathophysiology of SAD and potentially other anxiety and mood disorders. Fasedienol is pharmacologically active without requiring apparent systemic absorption and distribution of the compound to the brain to achieve its rapid-onset and short duration of anxiolytic effects.[/B][/I] [URL unfurl="true"]https://www.vistagen.com/news/videos[/URL] [B][ATTACH type="full" alt="Screenshot (33855).png"]42570[/ATTACH] [ATTACH type="full" alt="Screenshot (33856).png"]42571[/ATTACH] [ATTACH type="full" alt="Screenshot (33857).png"]42572[/ATTACH] [ATTACH type="full" alt="Screenshot (33859).png"]42573[/ATTACH][/B] [/QUOTE]
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Mental Health
On demand neuroactive nasal spray for social anxiety disorders
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