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Omicron - asymptomatic protocol?
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<blockquote data-quote="Vince" data-source="post: 215892" data-attributes="member: 843"><p><strong>Oslo, Norway—</strong>Vitamin K status is heavily associated with COVID-19-related inflammation—more strongly, in fact, than vitamin D deficiency, according to a new article published in <a href="https://www.frontiersin.org/articles/10.3389/fnut.2021.761191/full" target="_blank"><em>Frontiers in Nutrition</em>.</a></p><p></p><p>The article was written by a research group from the Canisius-Wilhelmina Hospital in the Netherlands, in collaboration with the vitamin K2 manufacturer Kappa Bioscience.</p><p></p><p></p><p>Pathology during COVID-19 infection arises partly from an excessive inflammatory response with a key role for IL-6. “IL-6 is a pro-inflammatory cytokine that plays a key role in the development of severe COVID-19 and is regarded as an important therapeutic target,” explained senior author Jona Walk, M.D., Ph.D., in a press release.</p><p></p><p>Both vitamins D and K have been proposed as potential modulators of this process. The research group in question assessed vitamin D and K status in 135 hospitalized COVID-19 patients in relation to inflammatory response, elastic fiber degradation, and clinical outcomes.</p><p></p><p>Comparing the patients with good outcomes and with poor outcomes:</p><p></p><ul> <li data-xf-list-type="ul">Vitamin D levels were not significantly different.</li> <li data-xf-list-type="ul">IL-6 levels were significantly higher in patients with a poor outcome.</li> <li data-xf-list-type="ul">Vitamin K status was associated with IL-6 levels, while vitamin D levels were only borderline statistically significantly correlated with IL-6.</li> <li data-xf-list-type="ul">A significant association was found between IL-6 and elastic fiber degradation.<ul> <li data-xf-list-type="ul">A significant association was found between IL-6 and elastic fiber degradation.</li> <li data-xf-list-type="ul">Contrary to vitamin K status, vitamin D did not correlate with elastic fiber degradation.</li> </ul></li> <li data-xf-list-type="ul">Pulmonologist and translational researcher Rob Janssen, M.D., Ph.D., stated: “There are many vitamin D proponents from scientists and medical doctors to influencers and eminent politicians, advocating the distribution of vitamin D among the general population to reduce the burden of COVID-19. However, administration of vitamin D without K may not be without risk, as vitamin D increases the demand for K. This may cause further vitamin K depletion, which could be harmful in patients with moderate or severe COVID-19 who are without exception already vitamin K deficient. Based on our current data and previous work, I strongly suggest that vitamin K2 should be added to D supplementation, particularly against the background of the ongoing pandemic.”<br /> <br /> The researchers have suggested an intervention trial to provide insight as to whether vitamin K administration, with or without vitamin D, could improve clinical outcomes in those with COVID-19</li> </ul><p></p><p>[URL unfurl="true"]https://wholefoodsmagazine.com/suppliers/news-suppliers/vitamin-k-status-correlates-with-covid-19-inflammation-research-finds/[/URL]</p></blockquote><p></p>
[QUOTE="Vince, post: 215892, member: 843"] [B]Oslo, Norway—[/B]Vitamin K status is heavily associated with COVID-19-related inflammation—more strongly, in fact, than vitamin D deficiency, according to a new article published in [URL='https://www.frontiersin.org/articles/10.3389/fnut.2021.761191/full'][I]Frontiers in Nutrition[/I].[/URL] The article was written by a research group from the Canisius-Wilhelmina Hospital in the Netherlands, in collaboration with the vitamin K2 manufacturer Kappa Bioscience. Pathology during COVID-19 infection arises partly from an excessive inflammatory response with a key role for IL-6. “IL-6 is a pro-inflammatory cytokine that plays a key role in the development of severe COVID-19 and is regarded as an important therapeutic target,” explained senior author Jona Walk, M.D., Ph.D., in a press release. Both vitamins D and K have been proposed as potential modulators of this process. The research group in question assessed vitamin D and K status in 135 hospitalized COVID-19 patients in relation to inflammatory response, elastic fiber degradation, and clinical outcomes. Comparing the patients with good outcomes and with poor outcomes: [LIST] [*]Vitamin D levels were not significantly different. [*]IL-6 levels were significantly higher in patients with a poor outcome. [*]Vitamin K status was associated with IL-6 levels, while vitamin D levels were only borderline statistically significantly correlated with IL-6. [*]A significant association was found between IL-6 and elastic fiber degradation. [LIST] [*]A significant association was found between IL-6 and elastic fiber degradation. [*]Contrary to vitamin K status, vitamin D did not correlate with elastic fiber degradation. [/LIST] [*]Pulmonologist and translational researcher Rob Janssen, M.D., Ph.D., stated: “There are many vitamin D proponents from scientists and medical doctors to influencers and eminent politicians, advocating the distribution of vitamin D among the general population to reduce the burden of COVID-19. However, administration of vitamin D without K may not be without risk, as vitamin D increases the demand for K. This may cause further vitamin K depletion, which could be harmful in patients with moderate or severe COVID-19 who are without exception already vitamin K deficient. Based on our current data and previous work, I strongly suggest that vitamin K2 should be added to D supplementation, particularly against the background of the ongoing pandemic.” The researchers have suggested an intervention trial to provide insight as to whether vitamin K administration, with or without vitamin D, could improve clinical outcomes in those with COVID-19 [/LIST] [URL unfurl="true"]https://wholefoodsmagazine.com/suppliers/news-suppliers/vitamin-k-status-correlates-with-covid-19-inflammation-research-finds/[/URL] [/QUOTE]
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Omicron - asymptomatic protocol?
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