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General Health & Fitness
Nutrition and Supplements
Omega-3s and cognition: dosage matters!
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<blockquote data-quote="Re-Ride" data-source="post: 27208" data-attributes="member: 8395"><p>Chris, anecdotal reports such as yours referencing joint pain are important. Vascepa is an Rx only omega containing EPA only. Joint pain is a common side effect. Perhaps the OTC products you tried had higher than expected EPA content. This is precisely my concern with OTC omega supplements. We have absolutely no idea what we are ingesting since OTC manufacturing has virtually no oversight or manufacturing standards. </p><p></p><p>Nelson's post was on DHA not "fish oil" or DHA/EPA purified compounds. Unless each and every study mentioned used the same compound all we have is an association not empirical data. The association of cognitive benefit by supplementing DHA>600 mg / day seems strong but consumers should be aware that highly purified DHA as omega-3-acid-ethyl esters or as omega-3-carboxylic acids is not the same as the DHA content claimed by OTC products. </p><p></p><p>The Rx omegas are specifically approved for lowering serum triglycerides >500 mg/dL. There is no conclusive proof that they prevent or treat heart disease. All omega supplementation is capable of causing serious blood clotting issues. Lovaza and likely supraphysiolgical dosing with OTC can cause elevated LDL "bad" cholesterol. </p><p></p><p>Rancidity: This may be an issue for many fish oils even before they make it in to the bottle. The raw material is pulverized fish scraps. Has your scaly friend been fresh squeezed? Assuming that it has there are still valid concerns that multi-bonded EFA's are quite fragile in vivo. Some researchers claim they scavenge oxygen from other parts of the body and/or promote diabetes. Anecdotally I have experienced both excessive bleeding and what seems to be hypoglycemia on 3 g Lovaza. </p><p></p><p>Members here tend to reject the overabundance of caution employed by the medical profession simply because many of us have suffered from refusal to prescribe TRT or hCG where not doing do resulted in unnecessary quality of life issues. </p><p></p><p>If and what to supplement when it comes to fish oil or omega isolates is a highly personal decision. </p><p></p><p>I am not promoting Peskin's POV, who appears to have no medical research credentials, but this makes an interesting listen: <a href="https://www.youtube.com/watch?v=Xuf5nFTtwEY" target="_blank">https://www.youtube.com/watch?v=Xuf5nFTtwEY</a></p></blockquote><p></p>
[QUOTE="Re-Ride, post: 27208, member: 8395"] Chris, anecdotal reports such as yours referencing joint pain are important. Vascepa is an Rx only omega containing EPA only. Joint pain is a common side effect. Perhaps the OTC products you tried had higher than expected EPA content. This is precisely my concern with OTC omega supplements. We have absolutely no idea what we are ingesting since OTC manufacturing has virtually no oversight or manufacturing standards. Nelson's post was on DHA not "fish oil" or DHA/EPA purified compounds. Unless each and every study mentioned used the same compound all we have is an association not empirical data. The association of cognitive benefit by supplementing DHA>600 mg / day seems strong but consumers should be aware that highly purified DHA as omega-3-acid-ethyl esters or as omega-3-carboxylic acids is not the same as the DHA content claimed by OTC products. The Rx omegas are specifically approved for lowering serum triglycerides >500 mg/dL. There is no conclusive proof that they prevent or treat heart disease. All omega supplementation is capable of causing serious blood clotting issues. Lovaza and likely supraphysiolgical dosing with OTC can cause elevated LDL "bad" cholesterol. Rancidity: This may be an issue for many fish oils even before they make it in to the bottle. The raw material is pulverized fish scraps. Has your scaly friend been fresh squeezed? Assuming that it has there are still valid concerns that multi-bonded EFA's are quite fragile in vivo. Some researchers claim they scavenge oxygen from other parts of the body and/or promote diabetes. Anecdotally I have experienced both excessive bleeding and what seems to be hypoglycemia on 3 g Lovaza. Members here tend to reject the overabundance of caution employed by the medical profession simply because many of us have suffered from refusal to prescribe TRT or hCG where not doing do resulted in unnecessary quality of life issues. If and what to supplement when it comes to fish oil or omega isolates is a highly personal decision. I am not promoting Peskin's POV, who appears to have no medical research credentials, but this makes an interesting listen: [url]https://www.youtube.com/watch?v=Xuf5nFTtwEY[/url] [/QUOTE]
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Omega-3s and cognition: dosage matters!
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