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Actually, yes. While I have been a big proponent of Natesto, this very issue is one of my motivations to try other forms of TRT. For me, it seems like it may be specific to a specific applicator - like the medicine doesn't come out as it should. I have on occasion bailed on an applicator and started a new one for this reason. In general, I think it's pretty uncommon to get a tube that does this. But, even with tubes that seem to dispense normally, I sometimes wonder if the dose is inconsistent based on circumstances: how far up the nostril you had the tip, do you have any congestion, did any leak out, etc.

All in all, I think dosing is mostly consistent, but likely less consistent than injections.

How long have you been on Natesto and how is it going (besides this issue)?