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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Official Natesto Thread
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<blockquote data-quote="Fortunate" data-source="post: 217339" data-attributes="member: 42264"><p>Natesto approaches TRT much differently than other forms. Instead of constant, high levels, like you said, you pulse your levels a few times during the day. As a result, you minimize suppression of the CNS signals, and therefore maintain some endogenous production. It also does not tend to elevate hematocrit or E2. My guess is that your levels simply aren't high enough for long enough to cause these side effects.</p><p></p><p>I don't think you are trying to reach a steady state with Natesto. You are simply pulsing T levels, thereby getting symptom relief and the subjective benefit of TRT. One upside is that, because you don't reach a steady state of constant high levels, you can stop using it and go back to your pre-treatment state and switch to something else if you want.</p><p></p><p>My subjective response to Natesto has been good. I think it's very useful for mood and, as above, I suspect it's good for libido. I have been jacking around so much for the last year, that I can't make a really good comment on what it does for body composition, but I am in decent shape. I suspect it's probably would not be an ideal choice for a body builder, though.</p><p></p><p>I did an experiment recently in which I checked my levels an hour after a dose. I was just below 500. Not terrible, but not as high as some studies report. However, I had stopped hCG for a few weeks just prior to doing this blood draw. Taking hCG doesn't make great sense while on Natesto, but I have been on it for years, and think I feel better on it. In any case, maybe this influenced my levels on the blood draw, assuming hCG has some CNS suppression of the axis. </p><p></p><p>Did you notice any benefit on it? Maybe you should try it twice a day.</p></blockquote><p></p>
[QUOTE="Fortunate, post: 217339, member: 42264"] Natesto approaches TRT much differently than other forms. Instead of constant, high levels, like you said, you pulse your levels a few times during the day. As a result, you minimize suppression of the CNS signals, and therefore maintain some endogenous production. It also does not tend to elevate hematocrit or E2. My guess is that your levels simply aren't high enough for long enough to cause these side effects. I don't think you are trying to reach a steady state with Natesto. You are simply pulsing T levels, thereby getting symptom relief and the subjective benefit of TRT. One upside is that, because you don't reach a steady state of constant high levels, you can stop using it and go back to your pre-treatment state and switch to something else if you want. My subjective response to Natesto has been good. I think it's very useful for mood and, as above, I suspect it's good for libido. I have been jacking around so much for the last year, that I can't make a really good comment on what it does for body composition, but I am in decent shape. I suspect it's probably would not be an ideal choice for a body builder, though. I did an experiment recently in which I checked my levels an hour after a dose. I was just below 500. Not terrible, but not as high as some studies report. However, I had stopped hCG for a few weeks just prior to doing this blood draw. Taking hCG doesn't make great sense while on Natesto, but I have been on it for years, and think I feel better on it. In any case, maybe this influenced my levels on the blood draw, assuming hCG has some CNS suppression of the axis. Did you notice any benefit on it? Maybe you should try it twice a day. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Official Natesto Thread
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