Obstructive Sleep Apnea: Diagnosis and Health Consequences

Nelson Vergel

Founder, ExcelMale.com
A good read for men too.


[FONT=&quot]Obstructive Sleep Apnea (OSA) can lead to oxidative stress, inflammatory processes, endothelial damage, sympathetic activation and metabolic dysregulation that predispose to atherosclerosis, and so OSA is a common cause of systemic hypertension.

During OSA, episodes of hypoxemia can drop the oxyhemoglobin saturation from 95% to 80%, depending on the length of the period of apnea [[/FONT]
8[FONT=&quot]]. OSA is an independent risk factor for cardiovascular and cerebrovascular diseases. Due to hypoxia, the oxidative stress leads to overproduction of reactive oxygen species which can cause endothelial dysfunction, resulting in atherosclerosis [[/FONT]9[FONT=&quot]]. The inflammatory marker C-reactive protein (CRP), tumor necrosis factor α (TNFα), and interleukin-6 (IL-6) were increased in patients with obstructive sleep apnea, and they were significantly higher in cases of severe obstructive sleep apnea, where the AHI was 15 or gr

 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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