Objective impacts of tadalafil on storage and voiding function in male patients with BPH: 1‑year outcomes from a prospective urodynamic study

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Objective impacts of tadalafil on storage and voiding function in male patients with benign prostatic hyperplasia: 1‑year outcomes from a prospective urodynamic study

Yoshihisa Matsukawa1 · Shun Takai1 · Tsuyoshi Majima1 · Yasuhito Funahashi1 · Naoto Sassa1 · Masashi Kato1 · Tokunori Yamamoto1 · Momokazu Gotoh1 Received: 17 May 2018 / Accepted: 14 August 2018 © Springer-Verlag GmbH Germany, part of Springer Nature 2018


Conclusions

The treatment with tadalafil for 12 months significantly relieved storage and voiding functions, along with LUTS, in patients diagnosed with LUTS/BPH. Monitoring the parameters of LUT function, such as bladder capacity, DO, Qmax, and BOOI, revealed that beneficial effects of tadalafil treatment observed at 3 months continued to improve until 12 months.
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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