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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Now with hCG, concerning bloodwork 7 months into TRT
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<blockquote data-quote="Mission" data-source="post: 127496" data-attributes="member: 18150"><p>Hoping to get some advice about my latest labs and protocol. I’m not sure what changes would be best at this point. I’m not confident in my TRT office and am considering switching docs. Anyway brief background….</p><p></p><p>Initial protocol and 1st labs after 7 weeks on TRT led to this:</p><p></p><p>Doing this twice per week…</p><p>50mg Tcyp subq</p><p>500IU hCG troche (sublingual)</p><p>0.25mg anastrozole</p><p></p><p>TT=848 (264-916)</p><p>FT(direct)=19.2 (8.7-25.1)</p><p>E2, sensitive=16 (8-35)</p><p>SHBG=48 (16.5-55.9)</p><p>CBC and metabolic tests all in range</p><p></p><p>That was about 5 months ago. I insisted the doc switch me to liquid hCG since there’s a lot of questions around the troches getting absorbed. I wanted to keep the testes alive, prevent shrinkage, and backfill other hormonal pathways – finally got the order. I wanted to lower my anastrozole dose after the last results but I figured if I’m taking real hCG, my e2 may go up and require the AI, so I kept that the same…</p><p></p><p>Doing this twice per week for the past 8 weeks now…</p><p>50mg Tcyp subq</p><p>500 IU hCG liquid subq at the time of T injection</p><p>0.25mg anastrozole</p><p></p><p>Recent bloodwork after a 12-hour fast. This was done in trough about 2 hours after I would usually dose. I was sure to be well-hydrated the day before and had a few glasses of water prior to the bw. Usual blood pressure these days is low 120s/70 and was that morning…</p><p></p><p>TT=964 (264-916) High</p><p>FT(direct)=25.4 (8.7-25.1) High</p><p>E2, sensitive=34.6 (8-35)</p><p>SHBG=40.0 (16.5-55.9)</p><p></p><p>I was pleased that H & H were okay…</p><p>Hemoglobin 16.7 (13.0-17.7)</p><p>Hematocrit 49.0 (37.5-51.0)</p><p></p><p>But my kidney results are concerning….</p><p>BUN 21 (6-20) High</p><p>Creatinine 1.50 (0.76-1.27) High </p><p>eGFR 59 (>59) Low</p><p>My creatinine has always hovered around the top of the range even before TRT, but BUN is usually low teens. I’m not an overly muscular dude – 170 lbs at 18% BF, 35 y/o. Don't take creatine supps and according to diet log, didn't have any protein powders since a week before bloods.</p><p></p><p>Everything else was in range other than slightly elevated cholesterol. What sparked me to get the followup bloodwork was I haven’t been feeling so hot the past 2-3 weeks. I feel a bit listless and unmotivated. My libido/desire is near 0 most days which is one of the main reasons I started TRT in the first place. A bit moody and easily irritated too. My workouts have been okay. I’ve been doing running and stationary bike HIIT, not much weight lifting recently. I did run a 3 miler the day before the bloodwork, though that’s an intermediate distance for me and causes no DOMS. Diet was changed about halfway between the 2 blood tests so for a while it’s been a net goal 1700 calories per day and I keep under 100g carbs/day (~80g is typical, all from fruit, vegetables, sweet potato). Of course I have the occasional weekend ‘slip’.</p><p></p><p>Aside from the kidneys I’m also concerned with my TT/FT being so high in a trough reading and my e2 creeping upwards. It seems this form of hCG I’m now taking is certainly doing something compared to that troche. Any advice would be appreciated</p></blockquote><p></p>
[QUOTE="Mission, post: 127496, member: 18150"] Hoping to get some advice about my latest labs and protocol. I’m not sure what changes would be best at this point. I’m not confident in my TRT office and am considering switching docs. Anyway brief background…. Initial protocol and 1st labs after 7 weeks on TRT led to this: Doing this twice per week… 50mg Tcyp subq 500IU hCG troche (sublingual) 0.25mg anastrozole TT=848 (264-916) FT(direct)=19.2 (8.7-25.1) E2, sensitive=16 (8-35) SHBG=48 (16.5-55.9) CBC and metabolic tests all in range That was about 5 months ago. I insisted the doc switch me to liquid hCG since there’s a lot of questions around the troches getting absorbed. I wanted to keep the testes alive, prevent shrinkage, and backfill other hormonal pathways – finally got the order. I wanted to lower my anastrozole dose after the last results but I figured if I’m taking real hCG, my e2 may go up and require the AI, so I kept that the same… Doing this twice per week for the past 8 weeks now… 50mg Tcyp subq 500 IU hCG liquid subq at the time of T injection 0.25mg anastrozole Recent bloodwork after a 12-hour fast. This was done in trough about 2 hours after I would usually dose. I was sure to be well-hydrated the day before and had a few glasses of water prior to the bw. Usual blood pressure these days is low 120s/70 and was that morning… TT=964 (264-916) High FT(direct)=25.4 (8.7-25.1) High E2, sensitive=34.6 (8-35) SHBG=40.0 (16.5-55.9) I was pleased that H & H were okay… Hemoglobin 16.7 (13.0-17.7) Hematocrit 49.0 (37.5-51.0) But my kidney results are concerning…. BUN 21 (6-20) High Creatinine 1.50 (0.76-1.27) High eGFR 59 (>59) Low My creatinine has always hovered around the top of the range even before TRT, but BUN is usually low teens. I’m not an overly muscular dude – 170 lbs at 18% BF, 35 y/o. Don't take creatine supps and according to diet log, didn't have any protein powders since a week before bloods. Everything else was in range other than slightly elevated cholesterol. What sparked me to get the followup bloodwork was I haven’t been feeling so hot the past 2-3 weeks. I feel a bit listless and unmotivated. My libido/desire is near 0 most days which is one of the main reasons I started TRT in the first place. A bit moody and easily irritated too. My workouts have been okay. I’ve been doing running and stationary bike HIIT, not much weight lifting recently. I did run a 3 miler the day before the bloodwork, though that’s an intermediate distance for me and causes no DOMS. Diet was changed about halfway between the 2 blood tests so for a while it’s been a net goal 1700 calories per day and I keep under 100g carbs/day (~80g is typical, all from fruit, vegetables, sweet potato). Of course I have the occasional weekend ‘slip’. Aside from the kidneys I’m also concerned with my TT/FT being so high in a trough reading and my e2 creeping upwards. It seems this form of hCG I’m now taking is certainly doing something compared to that troche. Any advice would be appreciated [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Now with hCG, concerning bloodwork 7 months into TRT
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