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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Novel perspectives of Testosterone Therapy in men with functional hypogonadism
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<blockquote data-quote="madman" data-source="post: 272265" data-attributes="member: 13851"><p><strong>8.1. Clinical relevance: a summary</strong></p><p><strong></strong></p><p><strong></strong></p><p><strong>1. Functional Hypogonadism and TTh Efficacy:</strong></p><p></p><p>�<em> TTh is effective in improving various metabolic parameters, such as insulin resistance and glycemic control, in men with functional hypogonadism, particularly those with obesity and T2D.</em></p><p></p><p></p><p><strong>2. Impact on Cardiovascular Health:</strong></p><p></p><p><em>� Most studies, including the TRAVERSE trial, show no significant increase in serious cardiovascular events with TTh. Some studies indicate a benefit regarding cardiovascular risk in younger men with metabolic disorders or Type 2 Diabetes Mellitus. The effects of TTh on Cardiovascular Risk are most likely dependent on baseline conditions and morbidity of hypogonadal patients.</em></p><p></p><p></p><p><strong>3. Bone Health Improvements:</strong></p><p></p><p><em>� TTh positively affects bone mineral density, especially in the lumbar spine, in hypogonadal men. It’s more effective in younger men and less effective compared to anti-osteoporosis drugs in older men with osteoporosis.</em></p><p></p><p></p><p><strong>4. Weight Management and T2D:</strong></p><p></p><p><em>� TTh, in combination with lifestyle modifications, can lead to significant weight loss, improved muscle mass, and reversal or prevention of recently diagnosed T2D, suggesting its potential role in managing obesity-associated hypogonadism.</em></p><p></p><p></p><p><strong>5. Long-Term Safety and Clinical Implications:</strong></p><p></p><p><em>�<strong> While short- to medium-term benefits of TTh are evident, there is a need for more research on its long-term safety, particularly in men with severe hypogonadism or significant cardiovascular risks.</strong></em></p></blockquote><p></p>
[QUOTE="madman, post: 272265, member: 13851"] [B]8.1. Clinical relevance: a summary 1. Functional Hypogonadism and TTh Efficacy:[/B] �[I] TTh is effective in improving various metabolic parameters, such as insulin resistance and glycemic control, in men with functional hypogonadism, particularly those with obesity and T2D.[/I] [B]2. Impact on Cardiovascular Health:[/B] [I]� Most studies, including the TRAVERSE trial, show no significant increase in serious cardiovascular events with TTh. Some studies indicate a benefit regarding cardiovascular risk in younger men with metabolic disorders or Type 2 Diabetes Mellitus. The effects of TTh on Cardiovascular Risk are most likely dependent on baseline conditions and morbidity of hypogonadal patients.[/I] [B]3. Bone Health Improvements:[/B] [I]� TTh positively affects bone mineral density, especially in the lumbar spine, in hypogonadal men. It’s more effective in younger men and less effective compared to anti-osteoporosis drugs in older men with osteoporosis.[/I] [B]4. Weight Management and T2D:[/B] [I]� TTh, in combination with lifestyle modifications, can lead to significant weight loss, improved muscle mass, and reversal or prevention of recently diagnosed T2D, suggesting its potential role in managing obesity-associated hypogonadism.[/I] [B]5. Long-Term Safety and Clinical Implications:[/B] [I]�[B] While short- to medium-term benefits of TTh are evident, there is a need for more research on its long-term safety, particularly in men with severe hypogonadism or significant cardiovascular risks.[/B][/I] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
Novel perspectives of Testosterone Therapy in men with functional hypogonadism
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