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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Not tolerating Test Prop?
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<blockquote data-quote="Cataceous" data-source="post: 162887" data-attributes="member: 38109"><p>I'd say that unmixed esters might be preferable only because the behavior is better understood. In my case I know that EOD enanthate by itself establishes an easily controllable, stable base level of testosterone. I've independently established the characteristics of daily propionate, so when I use both esters unmixed I think I have a pretty good idea of what serum testosterone is doing. But if the esters are mixed then the results aren't necessarily equivalent to a sum of the unmixed results. This is because the combination may well end up being like a single ester with a half-life in between that of the two constituents. If this is the case then it could be similar to phenylpropionate. But without testing, or a more detailed examination of theoretical considerations, it's just speculation.</p><p></p><p></p><p>Ok, 10.5 mg propionate has 8.8 mg testosterone (10.5 * 83.7%). So the equivalent dose of phenypropionate is 12.8 mg (8.8 / 68.6%). You are likely to see lower testosterone peaks and higher troughs with the change in ester. These changes will also be reflected in estradiol. I wish we had more information on the relative importance of peak estradiol versus average. This could give some insight into how various protocols would compare. Regarding a stabilization period, if we accept the phenylpropionate half-life figure of 1.5 days then you're looking at one or two weeks at most, using the rule-of-thumb of four or five half-lives to stabilize. If the half-life is actually longer then the adjustment period would also be longer.</p><p></p><p></p><p>If obtaining testosterone phenylpronionate is not a problem then I can't really think of any negatives. You'd still be getting the testosterone you need, it's just a question of whether the muted variation in levels gives better subjective results.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 162887, member: 38109"] I'd say that unmixed esters might be preferable only because the behavior is better understood. In my case I know that EOD enanthate by itself establishes an easily controllable, stable base level of testosterone. I've independently established the characteristics of daily propionate, so when I use both esters unmixed I think I have a pretty good idea of what serum testosterone is doing. But if the esters are mixed then the results aren't necessarily equivalent to a sum of the unmixed results. This is because the combination may well end up being like a single ester with a half-life in between that of the two constituents. If this is the case then it could be similar to phenylpropionate. But without testing, or a more detailed examination of theoretical considerations, it's just speculation. Ok, 10.5 mg propionate has 8.8 mg testosterone (10.5 * 83.7%). So the equivalent dose of phenypropionate is 12.8 mg (8.8 / 68.6%). You are likely to see lower testosterone peaks and higher troughs with the change in ester. These changes will also be reflected in estradiol. I wish we had more information on the relative importance of peak estradiol versus average. This could give some insight into how various protocols would compare. Regarding a stabilization period, if we accept the phenylpropionate half-life figure of 1.5 days then you're looking at one or two weeks at most, using the rule-of-thumb of four or five half-lives to stabilize. If the half-life is actually longer then the adjustment period would also be longer. If obtaining testosterone phenylpronionate is not a problem then I can't really think of any negatives. You'd still be getting the testosterone you need, it's just a question of whether the muted variation in levels gives better subjective results. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Not tolerating Test Prop?
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