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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Not so complex mathematical evidence for why Low Shbg men should inject more often.
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<blockquote data-quote="xqfq" data-source="post: 210689" data-attributes="member: 38167"><p>[ATTACH=full]17236[/ATTACH]</p><p>I am not sure if there are specifically studies on men on exogenous testosterone + an SHBG-lowering-agent.</p><p></p><p>I may dig further here later, but on my quick dip into research I found this paper describing studies on oral contraceptives in women (screenshot above), which raise SHBG and lower free testosterone. Note that in women, the production of testosterone is also held constant and is, I believe, mostly produced via DHEA from the adrenals.</p><p></p><p>Looking at the relative binding affinities of the sex hormones (e.g. DHT >> T >> E2) and the changes in SHBG levels between men and women, and before/after puberty, it seems like the body wants to use SHBG to limit androgen (and some estrogen) action.</p></blockquote><p></p>
[QUOTE="xqfq, post: 210689, member: 38167"] [ATTACH type="full"]17236[/ATTACH] I am not sure if there are specifically studies on men on exogenous testosterone + an SHBG-lowering-agent. I may dig further here later, but on my quick dip into research I found this paper describing studies on oral contraceptives in women (screenshot above), which raise SHBG and lower free testosterone. Note that in women, the production of testosterone is also held constant and is, I believe, mostly produced via DHEA from the adrenals. Looking at the relative binding affinities of the sex hormones (e.g. DHT >> T >> E2) and the changes in SHBG levels between men and women, and before/after puberty, it seems like the body wants to use SHBG to limit androgen (and some estrogen) action. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Not so complex mathematical evidence for why Low Shbg men should inject more often.
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