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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Not so complex mathematical evidence for why Low Shbg men should inject more often.
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<blockquote data-quote="xqfq" data-source="post: 210674" data-attributes="member: 38167"><p>1. Why do women with low SHBG experience hyperandrogenism?</p><p>2. Why are medications which increase SHBG used to treat hyperandrogenism? For instance, metformin and oral contraceptives.</p><p>3. Why do steroids which bind strongly to SHBG increase free testosterone levels for men on exogenous testosterone? For instance, proviron and DHT.</p><p></p><p>I wonder if you are assuming that SHBG is itself is constant. Obviously it's not - it is being produced and destroyed in the body somehow.</p><p></p><p>So if there is less SHBG, there are more free steroids. So SHBG is not a "drain" but more like a sushi boat in a sushi restaurant. The supply of sushi produced is constant, but with less boats available, more sushi is boat-free. It's not the case that every sushi roll on a boat will get eaten - some will be thrown out because they've been left out for too long.</p><p></p><p>Just my line of thinking, I am not sure either way on this yet.</p></blockquote><p></p>
[QUOTE="xqfq, post: 210674, member: 38167"] 1. Why do women with low SHBG experience hyperandrogenism? 2. Why are medications which increase SHBG used to treat hyperandrogenism? For instance, metformin and oral contraceptives. 3. Why do steroids which bind strongly to SHBG increase free testosterone levels for men on exogenous testosterone? For instance, proviron and DHT. I wonder if you are assuming that SHBG is itself is constant. Obviously it's not - it is being produced and destroyed in the body somehow. So if there is less SHBG, there are more free steroids. So SHBG is not a "drain" but more like a sushi boat in a sushi restaurant. The supply of sushi produced is constant, but with less boats available, more sushi is boat-free. It's not the case that every sushi roll on a boat will get eaten - some will be thrown out because they've been left out for too long. Just my line of thinking, I am not sure either way on this yet. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Not so complex mathematical evidence for why Low Shbg men should inject more often.
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