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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Nodule from SubQ Injections
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<blockquote data-quote="madman" data-source="post: 215905" data-attributes="member: 13851"><p>When it comes to injecting oil-based esterified T subcutaneously some individuals do not fare well as they tend to have a bad reaction (nodules, pain/swelling, itchiness).</p><p></p><p>Can be due to an allergic reaction to the excipients/carrier oil, ester used (more commonly propionate), or poor injection technique.</p><p></p><p>The volume of the oily solution and injection technique can play a big role.</p><p></p><p>Keeping injections to .5 ml (50 units) or less/injecting slow and steady can help minimize post-injection nodules.</p><p></p><p>Most nodules will resolve unless there is an infection.</p><p></p><p>Whether injecting sub-q/IM many may also run into issues with leakage of the oily solution/blood post-injection.</p><p></p><p>When using a fixed LDS insulin syringe 27-31G injection site leakage of the oily solution let alone blood should be<strong><em> minimal--->non-existant</em></strong> if using a proper injection technique.</p><p></p><p>Pushing hard on the plunger after injecting can cause the rubber stopper to compress causing a suction/vacuum effect (flow back) which can cause leakage of the oily solution.</p><p></p><p>Never force the plunger after injecting otherwise you will increase the chance of flow back.</p><p></p><p>Just inject <strong><em>slow and steady</em></strong> (less trauma) to surrounding tissue.</p><p></p><p>It is normal to sometimes get some blood leakage (minimal) let alone oily solution after injecting especially if you nicked a vessel on the way in or anytime you pierce the skin.</p><p></p><p>Avoid pressing hard on the plunger after injecting and it will make a big difference in preventing any flow back (oily solution/blood).</p><p></p><p>I find piercing the skin quick than injecting slow and steady with minimal pressure from start to finish works best.</p><p></p><p></p><p></p><p><strong><em><strong><em>I typically administer my HCG and HMG injections SubQ around the naval area - those <u>watery nodules disappear in half a day</u>, which I why I reserve my belly-button area for those.</em></strong></em></strong></p><p><strong><em></em></strong></p><p><strong><em>And, for a couple of years, I've administered my T injections SubQ around my love handles. I occasionally switch it up and do shallow IM in the ventro-gluteals; but, stick to love handles for the most part. I typically get a <u>small nodule under the skin for 24-48 hours where the oil is deposited</u>. <u>It doesn't cause any discomfort and is typically gone within a couple of days</u>.</em></strong></p><p></p><p>Seeing as you have issues with nodules after injecting oil-based let alone water-based medications subcutaneously then injecting shallow IM would make more sense.</p><p></p><p>Luckily you have not had any issues with absorption/effectiveness or major discomfort at the injection site up until now otherwise you would have bailed out on sub-q much sooner.</p><p></p><p></p><p><strong><em>However, on a recent injection, it felt a little more painful than normal - and upon removing the needle, a very dark-tinted blood trickled out. The pain was gone within a few hours. But, it's now <u>10 days later, I can still feel a sizable nodule under the skin where I injected</u>. <u>It's not painful - it's just there</u>. I'm concerned it could be some trapped oil that's not going away.</em></strong></p><p></p><p>Was anything done differently when you injected this time?</p><p></p><p>If it was infected you would know.</p><p></p><p>Even then 10 days post-injection is far too long and I would go have it looked at.</p><p></p><p></p><p></p><p></p><p><strong>*Regarding big pharma, generic or compounded injectable T there is no secret recipe as they are all manufactured with:</strong></p><p></p><p>- an <strong><em>esterified T (prodrug) </em></strong>whether (propionate/enanthate/cypionate/undecanoate or mixed esters)</p><p></p><p>- a <strong><em>carrier oil (vehiculum)</em> </strong>such as (sesame, cottonseed, castor, peanut, grapeseed)</p><p></p><p>- an <strong><em>excipient</em></strong> such as:</p><p></p><p></p><p><strong>Benzyl Alcohol</strong> </p><p>• Solubility enhancer </p><p>• Oil viscosity reducer </p><p>• Local anesthetic</p><p>• Preservative</p><p></p><p></p><p><strong>Benzyl Benzoate</strong> </p><p>• Solubility enhancer </p><p>• Solvent</p><p></p><p></p><p><strong>Ethanol </strong></p><p>• Solvent</p><p></p><p></p><p><strong>Chlorobutanol</strong> </p><p>• Preservative</p></blockquote><p></p>
[QUOTE="madman, post: 215905, member: 13851"] When it comes to injecting oil-based esterified T subcutaneously some individuals do not fare well as they tend to have a bad reaction (nodules, pain/swelling, itchiness). Can be due to an allergic reaction to the excipients/carrier oil, ester used (more commonly propionate), or poor injection technique. The volume of the oily solution and injection technique can play a big role. Keeping injections to .5 ml (50 units) or less/injecting slow and steady can help minimize post-injection nodules. Most nodules will resolve unless there is an infection. Whether injecting sub-q/IM many may also run into issues with leakage of the oily solution/blood post-injection. When using a fixed LDS insulin syringe 27-31G injection site leakage of the oily solution let alone blood should be[B][I] minimal--->non-existant[/I][/B] if using a proper injection technique. Pushing hard on the plunger after injecting can cause the rubber stopper to compress causing a suction/vacuum effect (flow back) which can cause leakage of the oily solution. Never force the plunger after injecting otherwise you will increase the chance of flow back. Just inject [B][I]slow and steady[/I][/B] (less trauma) to surrounding tissue. It is normal to sometimes get some blood leakage (minimal) let alone oily solution after injecting especially if you nicked a vessel on the way in or anytime you pierce the skin. Avoid pressing hard on the plunger after injecting and it will make a big difference in preventing any flow back (oily solution/blood). I find piercing the skin quick than injecting slow and steady with minimal pressure from start to finish works best. [B][I][B][I]I typically administer my HCG and HMG injections SubQ around the naval area - those [U]watery nodules disappear in half a day[/U], which I why I reserve my belly-button area for those.[/I][/B] And, for a couple of years, I've administered my T injections SubQ around my love handles. I occasionally switch it up and do shallow IM in the ventro-gluteals; but, stick to love handles for the most part. I typically get a [U]small nodule under the skin for 24-48 hours where the oil is deposited[/U]. [U]It doesn't cause any discomfort and is typically gone within a couple of days[/U].[/I][/B] Seeing as you have issues with nodules after injecting oil-based let alone water-based medications subcutaneously then injecting shallow IM would make more sense. Luckily you have not had any issues with absorption/effectiveness or major discomfort at the injection site up until now otherwise you would have bailed out on sub-q much sooner. [B][I]However, on a recent injection, it felt a little more painful than normal - and upon removing the needle, a very dark-tinted blood trickled out. The pain was gone within a few hours. But, it's now [U]10 days later, I can still feel a sizable nodule under the skin where I injected[/U]. [U]It's not painful - it's just there[/U]. I'm concerned it could be some trapped oil that's not going away.[/I][/B] Was anything done differently when you injected this time? If it was infected you would know. Even then 10 days post-injection is far too long and I would go have it looked at. [B]*Regarding big pharma, generic or compounded injectable T there is no secret recipe as they are all manufactured with:[/B] - an [B][I]esterified T (prodrug) [/I][/B]whether (propionate/enanthate/cypionate/undecanoate or mixed esters) - a [B][I]carrier oil (vehiculum)[/I] [/B]such as (sesame, cottonseed, castor, peanut, grapeseed) - an [B][I]excipient[/I][/B] such as: [B]Benzyl Alcohol[/B] • Solubility enhancer • Oil viscosity reducer • Local anesthetic • Preservative [B]Benzyl Benzoate[/B] • Solubility enhancer • Solvent [B]Ethanol [/B] • Solvent [B]Chlorobutanol[/B] • Preservative [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Nodule from SubQ Injections
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