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Niacin and Cholesterol
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<blockquote data-quote="Nelson Vergel" data-source="post: 1868" data-attributes="member: 3"><p>I have never been able to tolerate it in any form. Gladly I no longer have low HDL. It has a modest effect on LDL but its best effect is at raising HDL. Higher doses of testosterone or anabolic steroids can lower HDL (and triglycerides).</p><p></p><p>Here is a great reference:</p><p></p><p>Niacin decreases LDL-C levels by 5% to 25% and triglyceride levels by 20% to 50% (<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ira30031t1" target="_blank">Table 1</a>).<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-1" target="_blank">1</a>,<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-20" target="_blank">20</a></p><p></p><p>Niacin is the most effective pharmacologic agent currently on the market for raising HDL-C levels, with increases of 15% to 35%.<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-1" target="_blank">1</a> It follows a relatively flat dose-response curve<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-32" target="_blank">32</a> so most of the rise in HDL-C with niacin occurs at daily doses of 1 to 1.5 g (<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ira30031f2" target="_blank">Figure 2</a>).<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-14" target="_blank">14</a>,<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-18" target="_blank">18</a>,<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-20" target="_blank">20</a>,<a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-32" target="_blank">32</a></p><p></p><p><a href="http://archinte.jamanetwork.com/article.aspx?articleid=216937" target="_blank">http://archinte.jamanetwork.com/article.aspx?articleid=216937</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 1868, member: 3"] I have never been able to tolerate it in any form. Gladly I no longer have low HDL. It has a modest effect on LDL but its best effect is at raising HDL. Higher doses of testosterone or anabolic steroids can lower HDL (and triglycerides). Here is a great reference: Niacin decreases LDL-C levels by 5% to 25% and triglyceride levels by 20% to 50% ([URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ira30031t1"]Table 1[/URL]).[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-1"]1[/URL],[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-20"]20[/URL] Niacin is the most effective pharmacologic agent currently on the market for raising HDL-C levels, with increases of 15% to 35%.[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-1"]1[/URL] It follows a relatively flat dose-response curve[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-32"]32[/URL] so most of the rise in HDL-C with niacin occurs at daily doses of 1 to 1.5 g ([URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ira30031f2"]Figure 2[/URL]).[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-14"]14[/URL],[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-18"]18[/URL],[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-20"]20[/URL],[URL="http://archinte.jamanetwork.com/article.aspx?articleid=216937#ref-ira30031-32"]32[/URL] [URL]http://archinte.jamanetwork.com/article.aspx?articleid=216937[/URL] [/QUOTE]
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