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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Newish Study on HCT
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<blockquote data-quote="GreenMachineX" data-source="post: 226989" data-attributes="member: 15245"><p>Has anyone seen this? It looks like those with higher hct lived longer...</p><p>[URL unfurl="true"]https://www.liebertpub.com/doi/10.1089/andro.2021.0019[/URL]</p><p></p><h3>Testosterone Therapy: Increase in Hematocrit is Associated with Decreased Mortality</h3><p></p><p><strong><em>"Results:</em></strong> HCT increased significantly (median change at final assessment: +5.0%) in men on TTh. HCT was higher (<em>p</em> = 0.021, rank-sum test) in those alive than in those who died, although median values were identical (49.0%). Baseline HCT and Δ HCT were inversely associated with mortality after adjustment for age in both logistic and Cox regression models. Men with final HCT >49.0% (median) suffered lower mortality than men with HCT ≤49.0%.</p><p></p><p><strong><em>Conclusions:</em></strong> A median HCT increase of 5.0% was associated with TTh, mostly within 48 months of commencing therapy. An increase in HCT (up to 52.0% at final assessment) was independently associated with reduced mortality, indicating current guidelines using a HCT value of 54.0% as a threshold for management change are appropriate until further study."</p></blockquote><p></p>
[QUOTE="GreenMachineX, post: 226989, member: 15245"] Has anyone seen this? It looks like those with higher hct lived longer... [URL unfurl="true"]https://www.liebertpub.com/doi/10.1089/andro.2021.0019[/URL] [HEADING=2]Testosterone Therapy: Increase in Hematocrit is Associated with Decreased Mortality[/HEADING] [B][I]"Results:[/I][/B] HCT increased significantly (median change at final assessment: +5.0%) in men on TTh. HCT was higher ([I]p[/I] = 0.021, rank-sum test) in those alive than in those who died, although median values were identical (49.0%). Baseline HCT and Δ HCT were inversely associated with mortality after adjustment for age in both logistic and Cox regression models. Men with final HCT >49.0% (median) suffered lower mortality than men with HCT ≤49.0%. [B][I]Conclusions:[/I][/B] A median HCT increase of 5.0% was associated with TTh, mostly within 48 months of commencing therapy. An increase in HCT (up to 52.0% at final assessment) was independently associated with reduced mortality, indicating current guidelines using a HCT value of 54.0% as a threshold for management change are appropriate until further study." [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Newish Study on HCT
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