San Francisco user here. Subscribed to Helix and couldn't be happier.
A mobile phlebotomist visited my home, took my blood and I was off from there. A doctor was also sent to visit me at home for the physical, which finished my qualification.
I looked into Defy. I didn't follow-up with them because the costs of my lab work would have been quite high. Helix covers all blood work, and I appreciate the flat-fee pricing, which ultimately is a cheaper package for me. I also appreciated that a doctor visited me at my home to qualify me and do my physical.
I'm currently on test cyp, hcg and anastrozole. So far, a great experience.