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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
New thoughts on AI
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<blockquote data-quote="madman" data-source="post: 139366" data-attributes="member: 13851"><p>I would say it comes down to metabolic clearance rates determined by ones (SHBG/hepatic blood flow) between individuals.</p><p></p><p>Men with lower SHBG would notice a more drastic drop in T levels between peak/trough.</p><p></p><p>SHBG not only buffers serum testosterone levels but also decreases hepatic degradation.</p><p></p><p>As we know lower SHBG men will have a larger variation between peak/trough levels and tend to do much better injecting lower doses more frequently but even than I would say their peak/trough would me more drastic even on daily injections as oppose to one with normal SHBG.</p><p></p><p>The only true way to know how said dose of T used/injection frequency and choice of ester used will effect ones TT/FT/E2 and DHT levels would be to have blood work done frequently post injection to truly see how levels look 12/24/36/48 hrs and so on which is not feasible for most if we want to look at blood levels at many time points.</p><p></p><p>We can sit here and say peak/trough this and that but in the end as we know every individual is different and many factors come into play on what peak/trough levels one would achieve on said protocol (dose/injection frequency/ester used).</p><p></p><p>Blood work done frequently is the only way.</p></blockquote><p></p>
[QUOTE="madman, post: 139366, member: 13851"] I would say it comes down to metabolic clearance rates determined by ones (SHBG/hepatic blood flow) between individuals. Men with lower SHBG would notice a more drastic drop in T levels between peak/trough. SHBG not only buffers serum testosterone levels but also decreases hepatic degradation. As we know lower SHBG men will have a larger variation between peak/trough levels and tend to do much better injecting lower doses more frequently but even than I would say their peak/trough would me more drastic even on daily injections as oppose to one with normal SHBG. The only true way to know how said dose of T used/injection frequency and choice of ester used will effect ones TT/FT/E2 and DHT levels would be to have blood work done frequently post injection to truly see how levels look 12/24/36/48 hrs and so on which is not feasible for most if we want to look at blood levels at many time points. We can sit here and say peak/trough this and that but in the end as we know every individual is different and many factors come into play on what peak/trough levels one would achieve on said protocol (dose/injection frequency/ester used). Blood work done frequently is the only way. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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