In the past when I needed an AI to combat side effects it was from (i) long esters (ii) infrequent injections (iii) HCG (iv) DHEA (vi) too much body fat.
I feel best with frequent injections with short ester and nothing else.
I neither take AI, nor HCG, nor DHEA, nor Pregnenolone anymore.
Tested it all and for me doesn't improve the experience that I get from short ester applied frequently.
When I take long ester or HCG it's a different ballgame and I need at least an AI to feel half way good plus pregnenolone to combat brainfog.
If I still had side effects from high E2, I would try taking pregnenolone over an AI. It seems to reduce E2 for me via the progesterone pathway. But then with short ester and frequent injections I don't get there in the first place.
I have come to the conclusion if one needs AI to combat side effects, the protocol is not optimal for the person. Instead of trying to fix a suboptimal protocol with AI, the smarter move seems to be finding a better protocol. The most effective change I have found is using a short ester.
