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Cortisol is the first hormone you need to be sure that works properly because thyroid and TRT and most hormones needs adequate amounts of cortisol to function normally. So the rule of thumb is be sure cortisol is normal, if not get your new MD to work with you on that. Next hormone to get normal is thyroid. If you have elevated antibodies it can mean hashimoto's so you want to get that normalized as well. All that to be done before you start TRT. Since your wondering about cortisol the only way to eliminate your concern is to get the 4 x diurnal Saliva cortisol labs. This lab tells you what your cortisol levels are at the 4 different times of the day and paints a pretty clear picture of what your adrenals are doing. This is available at Discountedlabs.com

[QUOTE="ratbag, post: 116383, member: 972"] Cortisol is the first hormone you need to be sure that works properly because thyroid and TRT and most hormones needs adequate amounts of cortisol to function normally. So the rule of thumb is be sure cortisol is normal, if not get your new MD to work with you on that. Next hormone to get normal is thyroid. If you have elevated antibodies it can mean hashimoto's so you want to get that normalized as well. All that to be done before you start TRT. Since your wondering about cortisol the only way to eliminate your concern is to get the 4 x diurnal Saliva cortisol labs. This lab tells you what your cortisol levels are at the 4 different times of the day and paints a pretty clear picture of what your adrenals are doing. This is available at Discountedlabs.com [/QUOTE]