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First set labs your TT was 617 ng/dL using the most accurate assay LC-MS/MS but you did not show what your FT (using an accurate assay) or SHBG level was?

In the second set of labs, your TT is robust 840 ng/dL (not sure what assay was used), and your FT was done using an inaccurate assay so although your SHBG level is high which will have a big impact on your FT level (depending on how high SHBG is and where your TT levels sit) you have no idea where your FT level truly sits and it may not be as low as you think!

Again I would retest using an accurate assay for FT and always have testing done at the same lab, same time (early am) using the same assays (accurate) otherwise you are just wasting your time.

[QUOTE="madman, post: 189790, member: 13851"] First set labs your TT was 617 ng/dL using the most accurate assay LC-MS/MS but you did not show what your FT (using an accurate assay) or SHBG level was? In the second set of labs, your TT is robust 840 ng/dL (not sure what assay was used), and your FT was done using an inaccurate assay so although your SHBG level is high which will have a big impact on your FT level (depending on how high SHBG is and where your TT levels sit) you have no idea where your FT level truly sits and it may not be as low as you think! Again I would retest using an accurate assay for FT and always have testing done at the same lab, same time (early am) using the same assays (accurate) otherwise you are just wasting your time. [/QUOTE]

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038