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long time lurker, just decided to post to hopefully help out the OP... long story short, I aromatize big time and feel like crap at estradiol levels over about 30. I started TRT with just test cyp through my GP, then added HCG through Defy, DIM 3x a day, and no AI. I couldn't get my estradiol down enough to not feel like I was in menopause (felt hot all the time, moody AF, etc.). Started the AI through Defy and felt better within days, so I quit the DIM thinking the AI had it all under control and I didn't need the DIM anymore. Nope. Symptoms returned. My SHBG is about the same as yours, stays pretty much mid-range. Personally, I need the AI and the DIM to feel right and keep my estradiol levels in check. I get a DIM supplement off of amazon that recommends three caps a day at mealtime- I instead take one cap three times a day, and it works great for me. From what I understand, the AI helps to mediate (not prevent) the conversion of T to E, but DIM helps get it out of your system. Anyways, that's what worked for me! Good luck!