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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Need to understand the relationship between SHBG, Albumin, Free Test and Total test better
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<blockquote data-quote="Ardoc" data-source="post: 66049" data-attributes="member: 12171"><p>Sean I did have my SHBG tested once and it was 11.6 mol/l with a ref range of 10 - 30. At that time i was doing well on weekly injections. I will be testing again in a couple weeks. It seems there are as many (or more) people on this forum who are dealing with low SHBG although I may be paying more attention to those people as I think i'm in that boat. Certainly low-ish when tested.</p><p></p><p>CW thank you for taking the time to write such a detailed post. Its great that you give so much of your time to the members here!</p><p>Contrary to how it may come across I'm not stressed about it I'm just looking for some ideas.</p><p>a) Do I aim for high normal TT and accept FT over-range?</p><p>b) Do I aim for high normal FT and accept mid-level TT?</p><p>c) Do I try other things before moving to daily injections?</p><p></p><p>I think I just got confused about why I care about TT if a large % of it is permanently bound to SHBG and therefor unusable? Does this SHBG bound Test play another role? It seems like the more you "learn" the more you realize you don't know much about this.</p><p></p><p>I did well on weekly injections in the beginning when my SHBG was at the low end of normal. Then after i started to feel the benefits less, switched to E3.5D which was good for a time then had to switch to EOD. It "feels" as if my SHBG is decreasing over time? Total speculation and maybe i will be wrong when labs come back.</p><p></p><p>I am fine with "imperfect" numbers but since they are the sign posts guiding me to where I will feel the best, I'm trying to grasp which values to pay the most attention to as I'm trying to dial in. The only real frustrating part is I was initially lucky and with 120mg 1x/week, I was right at top end of TT and FT and my DHT was way over range and i felt great. It seems now like I have to "chase" the sweet spot continuously. I am ok with this, once I pick the number to target that works the best for me because it sure seems now like getting both TT and FT to the upper-range but not over isn't going to happen.</p><p>Did going from EOD to ED make much difference for you?</p></blockquote><p></p>
[QUOTE="Ardoc, post: 66049, member: 12171"] Sean I did have my SHBG tested once and it was 11.6 mol/l with a ref range of 10 - 30. At that time i was doing well on weekly injections. I will be testing again in a couple weeks. It seems there are as many (or more) people on this forum who are dealing with low SHBG although I may be paying more attention to those people as I think i'm in that boat. Certainly low-ish when tested. CW thank you for taking the time to write such a detailed post. Its great that you give so much of your time to the members here! Contrary to how it may come across I'm not stressed about it I'm just looking for some ideas. a) Do I aim for high normal TT and accept FT over-range? b) Do I aim for high normal FT and accept mid-level TT? c) Do I try other things before moving to daily injections? I think I just got confused about why I care about TT if a large % of it is permanently bound to SHBG and therefor unusable? Does this SHBG bound Test play another role? It seems like the more you "learn" the more you realize you don't know much about this. I did well on weekly injections in the beginning when my SHBG was at the low end of normal. Then after i started to feel the benefits less, switched to E3.5D which was good for a time then had to switch to EOD. It "feels" as if my SHBG is decreasing over time? Total speculation and maybe i will be wrong when labs come back. I am fine with "imperfect" numbers but since they are the sign posts guiding me to where I will feel the best, I'm trying to grasp which values to pay the most attention to as I'm trying to dial in. The only real frustrating part is I was initially lucky and with 120mg 1x/week, I was right at top end of TT and FT and my DHT was way over range and i felt great. It seems now like I have to "chase" the sweet spot continuously. I am ok with this, once I pick the number to target that works the best for me because it sure seems now like getting both TT and FT to the upper-range but not over isn't going to happen. Did going from EOD to ED make much difference for you? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Need to understand the relationship between SHBG, Albumin, Free Test and Total test better
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