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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Need advice on possible E2 crash.
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<blockquote data-quote="Mike9876" data-source="post: 147783" data-attributes="member: 18216"><p>I need some advice. I’ll try to keep this as short as possible with only relevant info. We tend to use different units here in Oz for things like Test and E2 so I will convert to the units you use there in US and Canada.</p><p></p><p>In early march I started to feel like I had symptoms of high e2. I had recently added in HCG to my protocol so this made sense. So I had a blood test. The blood taken on 11/03. My sensitive estradiol came back at 48.8pg/mL (13-40).</p><p></p><p>So I started taking anastrozole. Stupidly, I didn’t note down each time I took the AI. I was taking 0.25mg each time. I then had another test done on 01/04. My sensitive estradiol was now 28 (range same as previously). So now I continued to take the AI, but far less often. Again, stupidly, I didn’t note down when I took it. So I have no idea how much AI I’d taken. After another week or so I started to feel terrible, massive anxiety and also depression, so I had another blood test, this time the result was 20 (same range). BUT, and this is important. I had taken 0.25mg anastrozole the day before the blood test, 0.25mg 2 days before that, and another 0.25mg 2 days before that. So although my E2 came back at 20, would it be fair to conclude that those 3 doses of AI would have continued to lower my E2, and that over the next few days or a week, my E2 would have actually been much lower than the 20 that it was at the time of the blood test?</p><p></p><p>Weirdly, on that test that came back with the E2 of 20, my total testosterone was only 285 (518 on the previous test just 10 days earlier.)</p><p></p><p>I went through a period there for a week or more of horrible anxiety and depression. I am still having this now, although nowhere near as bad as before. I am having another blood test next week.</p><p></p><p>I would have thought that my E2 would have made it back to normal since it has been almost 4 weeks since my last AI. Or does it take longer than this?</p><p></p><p>My mental state is still pretty bad so any advice or info will be much appreciated.</p><p></p><p></p><p>p.s. I have definitely learned my lesson about being VERY cautious with AI’s!</p></blockquote><p></p>
[QUOTE="Mike9876, post: 147783, member: 18216"] I need some advice. I’ll try to keep this as short as possible with only relevant info. We tend to use different units here in Oz for things like Test and E2 so I will convert to the units you use there in US and Canada. In early march I started to feel like I had symptoms of high e2. I had recently added in HCG to my protocol so this made sense. So I had a blood test. The blood taken on 11/03. My sensitive estradiol came back at 48.8pg/mL (13-40). So I started taking anastrozole. Stupidly, I didn’t note down each time I took the AI. I was taking 0.25mg each time. I then had another test done on 01/04. My sensitive estradiol was now 28 (range same as previously). So now I continued to take the AI, but far less often. Again, stupidly, I didn’t note down when I took it. So I have no idea how much AI I’d taken. After another week or so I started to feel terrible, massive anxiety and also depression, so I had another blood test, this time the result was 20 (same range). BUT, and this is important. I had taken 0.25mg anastrozole the day before the blood test, 0.25mg 2 days before that, and another 0.25mg 2 days before that. So although my E2 came back at 20, would it be fair to conclude that those 3 doses of AI would have continued to lower my E2, and that over the next few days or a week, my E2 would have actually been much lower than the 20 that it was at the time of the blood test? Weirdly, on that test that came back with the E2 of 20, my total testosterone was only 285 (518 on the previous test just 10 days earlier.) I went through a period there for a week or more of horrible anxiety and depression. I am still having this now, although nowhere near as bad as before. I am having another blood test next week. I would have thought that my E2 would have made it back to normal since it has been almost 4 weeks since my last AI. Or does it take longer than this? My mental state is still pretty bad so any advice or info will be much appreciated. p.s. I have definitely learned my lesson about being VERY cautious with AI’s! [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Need advice on possible E2 crash.
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