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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Need advice on Anastrozole dosage
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<blockquote data-quote="MarkM" data-source="post: 119984"><p>Hi Mike,</p><p></p><p>I'm with you in that normally it seems anxiety happens when E2 is depressed and gets too low but you feel like you are experiencing it with high E2. These symptoms can effect each us us differently depending on our own body chemistry. The EOD injection protocol is probably good with SHBG of 21 but you might try injecting ED and see if that helps. With low SHBG you are also going to be having high Free Estradiol too. That may be where the anxiety is coming from.</p><p></p><p>A lot of low SHBG guys seem to do better when they run Total T in the 600 to 700 range and they Free T just closer to the mid range to 3/4 mark of the upper limit verse being over the top of the upper limit like you are. With that high Free T you are getting high Free E. Injecting daily might help the estradiol from spiking as high. The non-sensitive E2 test is not very accurate for men but regardless you seem to have symptoms. I believe the Estradiol Sensitive test in Australia is called "Oestradiol LCMS".</p><p></p><p>If you have the sensitive test available, which I believe you do, that would help. It's hard to extrapolate what the non-sensitive would equate to in sensitive estradiol terms. My non-sensitive E2 is 91 and sensitive is 35. [USER=2657]@Vince Carter[/USER] a low SHBG forum member believes that low SHBG guys need their E2 close to their SHBG. </p><p></p><p>[USER=2657]@Vince Carter[/USER] has looked into this more than anyone else and maybe he will chime in. </p><p></p><p>Right now, if you are feeling bad, go back on the AI in hopes of feeling better until you get this worked out. I am not a fan of AI's but I realize some people need them and if they need them they should take them.</p></blockquote><p></p>
[QUOTE="MarkM, post: 119984"] Hi Mike, I'm with you in that normally it seems anxiety happens when E2 is depressed and gets too low but you feel like you are experiencing it with high E2. These symptoms can effect each us us differently depending on our own body chemistry. The EOD injection protocol is probably good with SHBG of 21 but you might try injecting ED and see if that helps. With low SHBG you are also going to be having high Free Estradiol too. That may be where the anxiety is coming from. A lot of low SHBG guys seem to do better when they run Total T in the 600 to 700 range and they Free T just closer to the mid range to 3/4 mark of the upper limit verse being over the top of the upper limit like you are. With that high Free T you are getting high Free E. Injecting daily might help the estradiol from spiking as high. The non-sensitive E2 test is not very accurate for men but regardless you seem to have symptoms. I believe the Estradiol Sensitive test in Australia is called "Oestradiol LCMS". If you have the sensitive test available, which I believe you do, that would help. It's hard to extrapolate what the non-sensitive would equate to in sensitive estradiol terms. My non-sensitive E2 is 91 and sensitive is 35. [USER=2657]@Vince Carter[/USER] a low SHBG forum member believes that low SHBG guys need their E2 close to their SHBG. [USER=2657]@Vince Carter[/USER] has looked into this more than anyone else and maybe he will chime in. Right now, if you are feeling bad, go back on the AI in hopes of feeling better until you get this worked out. I am not a fan of AI's but I realize some people need them and if they need them they should take them. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Need advice on Anastrozole dosage
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