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Even though my HPTA is beyond restart due to age, high SHBG and time on TRT I went with Natesto as a way to solve some of the problems I was having with injections, namely terrible acne and inability to sleep more than four hours a night. It did work for both of those things but what I found was the test levels achieved could not overcome my relatively high SHBG so with the advice of my doctor I added test cream applied to the scrotum once a day (50 mg). Those two together have been the best form of test replacement I have experienced. My insurance pays for the Natesto I only pay for the cream.