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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Natesto + Clomid
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<blockquote data-quote="BigBeard411" data-source="post: 251675" data-attributes="member: 43898"><p>Fortunate, I spent a lot of time thinking about this. I read all the research papers I could find (I am a researcher by trade) on Natesto. I came to the conclusion that anatomical differences in a person's nose will greatly, and obviously, impact Total T after dosing (45min post administration). Placement of gel also impacts absorption in terms of speed. However, it seems like the recommend applying it to the soft tissue (basically interior lateral side of nostrils) where there is less vasculature. I think this may slow the absorption rate and allow for a broader spike and decline, as opposed to applying deeper inside (think about how people snort drugs) which prob causes a very quick and high peak that will also drop quickly. We need more sustained levels to feel better.</p><p></p><p>Sure, mucus can certainly affect absorption if it lines your nose. I think the brochure does advise to blow your nose prior to application. Hair may impact it, as some gel can cling to your hair as opposed to the wall of the nose. If you have a forest in there, then sure, use a nose trimmer.</p><p></p><p>And yes, i do notice variability in tubes. Not sure about dosage, but early on I did notice the amount coming out was not consistent. I complained a few times about this, but lately, things have been perfect with the tubes. </p><p></p><p>I did notice on natesto that my free T is higher than prior to Natesto usage, and it keep increasing every few months when I get blood work.</p><p></p><p>I took my 4th dose of clomid yesterday, (50mg 3x per week) and so far I have been feeling pretty great. Too soon to tell if this will persist. If you read below, you will see prior to TRT my test and LH fluctuates to below normal levels persistently, which resulted in many years of fluctuations energy/mood/focus.</p><p></p><p></p><p>Well libido is not the only thing. Over the past few years, my body has been feeling more and more run down. Worst symptom was probably severe brain fog and lack of energy/motivation. I work in a field that requires a lot of focus and mental clarity. My work progress greatly stagnated because of how bad I felt. I became very irritable too; this strained my relationships. </p><p></p><p>I had day to day fluctuations - sometimes I felt great and other times I felt absolutely horrible. It was the dips into feeling "horrible" that made me consider TRT for a long time - something I thought about for years.</p><p></p><p>After multiple test I found my testosterone fluctuates quite a bit - from low 200s to mid 400s. I think when I feel bad, it is when the test is low. Once I began Natesto, I no longer experienced any of the symptoms above for some months. It did work great, but it does not boost your T anywhere near TRT levels and symptom relief varies on absorption and current levels. I think this is my issue since my levels fluctuate a lot. Some days i would literally feel like a mental zombie all day. </p><p></p><p>The only thing I had going for me was the mental libido - it was always great. </p><p></p><p> I know my balls still work, but something was wrong. I did find out I had high prolactin, which now normalized, and it is not from a tumor. So it could be something wrong with my brain, and not my balls. My LH and FSH levels are the same as they were one year ago prior to treatment (on the low end). This is why I also opted for a therapy that does not shut you down - Natesto.</p></blockquote><p></p>
[QUOTE="BigBeard411, post: 251675, member: 43898"] Fortunate, I spent a lot of time thinking about this. I read all the research papers I could find (I am a researcher by trade) on Natesto. I came to the conclusion that anatomical differences in a person's nose will greatly, and obviously, impact Total T after dosing (45min post administration). Placement of gel also impacts absorption in terms of speed. However, it seems like the recommend applying it to the soft tissue (basically interior lateral side of nostrils) where there is less vasculature. I think this may slow the absorption rate and allow for a broader spike and decline, as opposed to applying deeper inside (think about how people snort drugs) which prob causes a very quick and high peak that will also drop quickly. We need more sustained levels to feel better. Sure, mucus can certainly affect absorption if it lines your nose. I think the brochure does advise to blow your nose prior to application. Hair may impact it, as some gel can cling to your hair as opposed to the wall of the nose. If you have a forest in there, then sure, use a nose trimmer. And yes, i do notice variability in tubes. Not sure about dosage, but early on I did notice the amount coming out was not consistent. I complained a few times about this, but lately, things have been perfect with the tubes. I did notice on natesto that my free T is higher than prior to Natesto usage, and it keep increasing every few months when I get blood work. I took my 4th dose of clomid yesterday, (50mg 3x per week) and so far I have been feeling pretty great. Too soon to tell if this will persist. If you read below, you will see prior to TRT my test and LH fluctuates to below normal levels persistently, which resulted in many years of fluctuations energy/mood/focus. Well libido is not the only thing. Over the past few years, my body has been feeling more and more run down. Worst symptom was probably severe brain fog and lack of energy/motivation. I work in a field that requires a lot of focus and mental clarity. My work progress greatly stagnated because of how bad I felt. I became very irritable too; this strained my relationships. I had day to day fluctuations - sometimes I felt great and other times I felt absolutely horrible. It was the dips into feeling "horrible" that made me consider TRT for a long time - something I thought about for years. After multiple test I found my testosterone fluctuates quite a bit - from low 200s to mid 400s. I think when I feel bad, it is when the test is low. Once I began Natesto, I no longer experienced any of the symptoms above for some months. It did work great, but it does not boost your T anywhere near TRT levels and symptom relief varies on absorption and current levels. I think this is my issue since my levels fluctuate a lot. Some days i would literally feel like a mental zombie all day. The only thing I had going for me was the mental libido - it was always great. I know my balls still work, but something was wrong. I did find out I had high prolactin, which now normalized, and it is not from a tumor. So it could be something wrong with my brain, and not my balls. My LH and FSH levels are the same as they were one year ago prior to treatment (on the low end). This is why I also opted for a therapy that does not shut you down - Natesto. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Natesto + Clomid
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