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Significantly lower serum melatonin levels were observed in CLL patients compared to healthy subjects. Patient had misalignment of the internal clock with the external light–dark cycle. The circadian rhythm of melatonin was disrupted, and the levels of melatonin were low compared to healthy subjects.

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National Center for Biotechnology Information › pmc

Melatonin: does it have utility in the treatment of haematological neoplasms?


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