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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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<blockquote data-quote="tareload" data-source="post: 216727"><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/trt-to-supraphysiological-levels-for-body-building.24696/post-216557[/URL]</p><p></p><p>[ATTACH=full]19497[/ATTACH]</p><p></p><p></p><p>Please see the HEDs (human equivalent doses) estimated in the table linked above. You can't simply compare the mg/kg used in the rodent studies and use that same mg/kg for what a human would take. This is a common mistake when folks not skilled in the art try to interpret these studies. Perpetuating this error in analysis only further reinforces misinformation among those trying to learn.</p><p></p><p>For example, for a rat you'd take the mg/kg from rat study and then divide that by ~6 to calculate an equivalent human mg/kg based on body surface area. Is this perfect? Absolutely not. There are volumes written about the transfer of rodent toxicology data to humans.</p><p></p><p>However, if you look at the estimated HEDs (for example 90 kg human) above in mg/week after properly translating the rodent research, the estimated dosages per week should give a reasonable individual pause. You can also take a look at the graphs I made for testosterone later in the thread I linked above.</p></blockquote><p></p>
[QUOTE="tareload, post: 216727"] [URL unfurl="true"]https://www.excelmale.com/forum/threads/trt-to-supraphysiological-levels-for-body-building.24696/post-216557[/URL] [ATTACH type="full" alt="1643902803756.png"]19497[/ATTACH] Please see the HEDs (human equivalent doses) estimated in the table linked above. You can't simply compare the mg/kg used in the rodent studies and use that same mg/kg for what a human would take. This is a common mistake when folks not skilled in the art try to interpret these studies. Perpetuating this error in analysis only further reinforces misinformation among those trying to learn. For example, for a rat you'd take the mg/kg from rat study and then divide that by ~6 to calculate an equivalent human mg/kg based on body surface area. Is this perfect? Absolutely not. There are volumes written about the transfer of rodent toxicology data to humans. However, if you look at the estimated HEDs (for example 90 kg human) above in mg/week after properly translating the rodent research, the estimated dosages per week should give a reasonable individual pause. You can also take a look at the graphs I made for testosterone later in the thread I linked above. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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