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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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<blockquote data-quote="benaoao" data-source="post: 176097" data-attributes="member: 40482"><p>I think it's safe to say that prolactin goes up as estrogen content in tissue goes up.</p><p></p><p>Perhaps it's the increased free E2 from 19nor use, since SHBG can drop to single digits. I'm not sure.</p><p></p><p>The abstract below got me wondering - Perhaps it's nandrolone itself being estrogenic with cumulative high doses?</p><p></p><p><a href="https://sci-hub.tw/https://www.ncbi.nlm.nih.gov/pubmed/15276617" target="_blank">Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different ... - PubMed - NCBI</a></p><p></p><p></p><p></p><p>However, table 1 shows "relative estrogenic potency" of Nandrolone to be a million times less than E2! 1000 times less than estriol... That's not very estrogenic if you ask me, however clear the dose-response is.</p><p></p><p>Have you guys ever seen this study? Their way to quantify anabolic steroid binding to multiple receptors is super interesting IMO. I'm drawn towards Nandrolone's affinity to the PR doing <em>something with regards to side effects</em>. I just don't know what.</p><p></p><p><a href="https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0003267008016139?via%3Dihub" target="_blank">https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0003267008016139?via=ihub</a></p></blockquote><p></p>
[QUOTE="benaoao, post: 176097, member: 40482"] I think it's safe to say that prolactin goes up as estrogen content in tissue goes up. Perhaps it's the increased free E2 from 19nor use, since SHBG can drop to single digits. I'm not sure. The abstract below got me wondering - Perhaps it's nandrolone itself being estrogenic with cumulative high doses? [URL='https://sci-hub.tw/https://www.ncbi.nlm.nih.gov/pubmed/15276617']Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different ... - PubMed - NCBI[/URL] However, table 1 shows "relative estrogenic potency" of Nandrolone to be a million times less than E2! 1000 times less than estriol... That's not very estrogenic if you ask me, however clear the dose-response is. Have you guys ever seen this study? Their way to quantify anabolic steroid binding to multiple receptors is super interesting IMO. I'm drawn towards Nandrolone's affinity to the PR doing [I]something with regards to side effects[/I]. I just don't know what. [URL='https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0003267008016139?via%3Dihub']https://sci-hub.tw/https://www.sciencedirect.com/science/article/pii/S0003267008016139?via=ihub[/URL] [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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