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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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<blockquote data-quote="DS3" data-source="post: 170135" data-attributes="member: 18514"><p>And you may be right. Given anecdotal stories from guys like the founder of this forum, Nelson Vergel, along with other instances of guys taking nandrolone for TRT purposes or enhancement purposes, it may not be that ALL guys will experience short-term memory issues with nandrolone administration. However, given the anecdotes of guys like myself that experience pronounced short-term memory deficits with its administration, along with mammalian studies discussing neural changes seen within the hippocampus during nandrolone administration, the likelihood that some people will experience pronounced short-term memory deficits while others will likely experience moderate or minimal deficits is probable.</p><p></p><p>I would hypothesize that if the results of mammalian studies that demonstrate negative effects on hippocampal function during nandrolone administration hold true in future studies on humans, many if not most users will experience short-term memory deficits as a result of negative changes that occur within the hippocampus. (Regardless of whether they were perceptive enough to report on it or not). </p><p></p><p>I would also posit that studies done on HIV patients taking nandrolone would not be concerned with memory function, nor would the HIV patients taking nandrolone to combat cachexia. Researchers would certainly note whether vital health markers such as BP, cholesterol, and hematocrit were within a healthy range, but administering memory and cognitive assessments to determine the net effect nandrolone has on memory and cognitive function would not be something that researchers conducting these studies would have time or resources for. </p><p></p><p><a href="https://www.sciencedirect.com/science/article/abs/pii/S0018506X12002450" target="_blank">Voluntary exercise does not ameliorate spatial learning and memory deficits induced by chronic administration of nandrolone decanoate in rats - ScienceDirect</a> (memory impairment in rats with chronic administration)</p><p><a href="https://academic.oup.com/ijnp/article/11/7/925/786119" target="_blank">Nandrolone abuse decreases anxiety and impairs memory in rats via central androgenic receptors</a> (memory impairment in rats with chronic administration)</p><p><a href="https://www.sciencedirect.com/science/article/abs/pii/S0304394009012695" target="_blank">Nandrolone decanoate administration elevates hippocampal prodynorphin mRNA expression and impairs Morris water maze performance in male rats - ScienceDirect</a> (memory impairment in rats via dynorphinergic actions)</p><p></p><p>*There are numerous studies out there demonstrating the negative effects that nandrolone administration has on hippocampal function and overall memory in mammals. A simple Google Scholar search will yield more than you bargained for.</p></blockquote><p></p>
[QUOTE="DS3, post: 170135, member: 18514"] And you may be right. Given anecdotal stories from guys like the founder of this forum, Nelson Vergel, along with other instances of guys taking nandrolone for TRT purposes or enhancement purposes, it may not be that ALL guys will experience short-term memory issues with nandrolone administration. However, given the anecdotes of guys like myself that experience pronounced short-term memory deficits with its administration, along with mammalian studies discussing neural changes seen within the hippocampus during nandrolone administration, the likelihood that some people will experience pronounced short-term memory deficits while others will likely experience moderate or minimal deficits is probable. I would hypothesize that if the results of mammalian studies that demonstrate negative effects on hippocampal function during nandrolone administration hold true in future studies on humans, many if not most users will experience short-term memory deficits as a result of negative changes that occur within the hippocampus. (Regardless of whether they were perceptive enough to report on it or not). I would also posit that studies done on HIV patients taking nandrolone would not be concerned with memory function, nor would the HIV patients taking nandrolone to combat cachexia. Researchers would certainly note whether vital health markers such as BP, cholesterol, and hematocrit were within a healthy range, but administering memory and cognitive assessments to determine the net effect nandrolone has on memory and cognitive function would not be something that researchers conducting these studies would have time or resources for. [URL="https://www.sciencedirect.com/science/article/abs/pii/S0018506X12002450"]Voluntary exercise does not ameliorate spatial learning and memory deficits induced by chronic administration of nandrolone decanoate in rats - ScienceDirect[/URL] (memory impairment in rats with chronic administration) [URL="https://academic.oup.com/ijnp/article/11/7/925/786119"]Nandrolone abuse decreases anxiety and impairs memory in rats via central androgenic receptors[/URL] (memory impairment in rats with chronic administration) [URL="https://www.sciencedirect.com/science/article/abs/pii/S0304394009012695"]Nandrolone decanoate administration elevates hippocampal prodynorphin mRNA expression and impairs Morris water maze performance in male rats - ScienceDirect[/URL] (memory impairment in rats via dynorphinergic actions) *There are numerous studies out there demonstrating the negative effects that nandrolone administration has on hippocampal function and overall memory in mammals. A simple Google Scholar search will yield more than you bargained for. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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