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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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<blockquote data-quote="Jason Sypolt" data-source="post: 168869" data-attributes="member: 13328"><p>No, an androgen can't lower exogenous T because there is really no way to do that - you are getting what you inject, apply, etc. into the body and nothing is going to stop that - absorption rates, digestion, and things like that aside. What the other androgens will do is compete with T for androgen receptors and SHBG as well as lower SHBG which can give you some strange-looking lab results if you aren't expecting that such as crazy high T or a Total T that is half what you thought. Therein lies the importance of being thorough with your lab follow ups if you really want to see and understand what is going on and not just base what you are doing off of how you feel and partial assumptions. I had a draw for my follow up labs this morning and it was 7 tubes for my large protocol.</p><p></p><p>Androgens will lower endogenous T, that is what your body naturally produces. The negative feedback loop that controls this process is sensitive to more than T alone. There have been some instances of substituting testosterone in TRT with Nandrolone or SARM's. But I have never seen an instance of it working out well, let alone as being considered for a life-long treatment, and I don't think that there is currently enough understanding and data on the subject. DHT derivatives and metabolites will give you a lot of the same benefits of T and in some cases exhibit even more powerful effects so it makes logical sense, but the body also seems to require T specifically and the other androgens can't replicate that closely enough. So you end up with side effects like the well-known ED from Nandrolone. That happens when not enough (or zero) T is used along with it. With enough T however, Nandrolone has definitely boosted my own libido. Like anything else, doses and then results from those will also vary from person to person.</p></blockquote><p></p>
[QUOTE="Jason Sypolt, post: 168869, member: 13328"] No, an androgen can't lower exogenous T because there is really no way to do that - you are getting what you inject, apply, etc. into the body and nothing is going to stop that - absorption rates, digestion, and things like that aside. What the other androgens will do is compete with T for androgen receptors and SHBG as well as lower SHBG which can give you some strange-looking lab results if you aren't expecting that such as crazy high T or a Total T that is half what you thought. Therein lies the importance of being thorough with your lab follow ups if you really want to see and understand what is going on and not just base what you are doing off of how you feel and partial assumptions. I had a draw for my follow up labs this morning and it was 7 tubes for my large protocol. Androgens will lower endogenous T, that is what your body naturally produces. The negative feedback loop that controls this process is sensitive to more than T alone. There have been some instances of substituting testosterone in TRT with Nandrolone or SARM's. But I have never seen an instance of it working out well, let alone as being considered for a life-long treatment, and I don't think that there is currently enough understanding and data on the subject. DHT derivatives and metabolites will give you a lot of the same benefits of T and in some cases exhibit even more powerful effects so it makes logical sense, but the body also seems to require T specifically and the other androgens can't replicate that closely enough. So you end up with side effects like the well-known ED from Nandrolone. That happens when not enough (or zero) T is used along with it. With enough T however, Nandrolone has definitely boosted my own libido. Like anything else, doses and then results from those will also vary from person to person. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone Experiences
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