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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Nandrolone added to TRT to reduce DHT?
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<blockquote data-quote="madman" data-source="post: 172406" data-attributes="member: 13851"><p>Nelson replied:</p><p></p><p><a href="https://www.excelmale.com/forum/threads/nandrolone-added-to-trt-to-reduce-dht.20537/post-172311" target="_blank">Friday at 4:43 PM</a></p><p><a href="https://www.excelmale.com/forum/threads/nandrolone-added-to-trt-to-reduce-dht.20537/post-172311" target="_blank">#23</a></p><p><span style="color: rgb(184, 49, 47)"><strong>Nandrolone, even as monotherapy, can increase acne like any anabolic steroid used alone or with testosterone.</strong></span> Some men are prone to acne. Some do not get acne at all. Here are some good discussions on how to minimize sebum build up that can lead to acne:</p><p></p><p><a href="https://www.google.com/search?q=acne+excelmale.co+site:www.excelmale.com&sa=X&ved=2ahUKEwi8u-XU2-PnAhUD-6wKHRA0AnUQrQIoBDAAegQIBxAP&biw=1500&bih=809&dpr=2" target="_blank">Acne on testosterone and anabolic steroids</a></p><p></p><p></p><p>To add to that point:</p><p></p><p><strong>William Llewellyn’s book:</strong></p><p><strong>ANABOLICS</strong></p><p></p><p></p><p><span style="color: rgb(184, 49, 47)">"As mentioned, testosterone also elicits <strong>androgenic activity, which occurs by its activating receptors in what are considered to be androgen responsive tissues </strong>(often through prior conversion to dihydrotestosterone. See DHT Conversion).</span> This includes the sebaceous glands, which are responsible for the secretion of oils in the skin. As the androgen level rises, so does the release of oils. As oil output increases, so does the chance for pores becoming clogged (we can see why acne is such a common side effect of steroid use). The production of body and facial hair is also linked to androgen receptor activation in skin and scalp tissues. This becomes most noticeable as boys mature into puberty, a period when testosterone levels rise rapidly, and androgen activity begins to stimulate the growth of hair on the body and face. <strong><span style="color: rgb(44, 130, 201)">Some time later in life, and with the contribution of a genetic predisposition, androgen activity in the scalp may also help to initiate male-pattern hair loss.</span></strong> <span style="color: rgb(184, 49, 47)"><strong>It is a misconception that dihydrotestosterone is an isolated culprit in the promotion of hair loss, </strong></span><span style="color: rgb(44, 130, 201)"><strong>however; as in actuality it is the general activation of the androgen receptor that is to blame (see DHT Conversion).</strong> </span>The functioning of sex glands and libido are also tied to the activity of androgens, as are numerous other regions of the central nervous/neuromuscular system"</p><p></p><p></p><p><strong>DHT and Androgenic Side Effects</strong></p><p></p><p>"In some regards, this local potentiation of testosterone's activity may be unwelcome, as higher androgenic activity in certain tissues may produce a number of undesirable side effects. <span style="color: rgb(184, 49, 47)"><strong>Acne, for example, is often triggered by dihydrotestosterone activity in the sebaceous glands, and the local formation of dihydrotestosterone in the scalp is typically blamed for triggering male pattern hair loss. </strong></span><span style="color: rgb(26, 188, 156)"><strong>You should know that it is a terrible misconception among bodybuilders that dihydrotestosterone is an isolated culprit when it comes to these side effects.</strong></span> <span style="color: rgb(44, 130, 201)"><strong>All anabolic/androgenic steroids exert their activities, both anabolic and androgenic, through the same cellular androgen receptor"</strong></span></p><p></p><p><strong><span style="color: rgb(184, 49, 47)">"Dihydrotestosterone is no different than any other steroid except that it is a more potent activator of this receptor than most, and can be formed locally in certain androgen-sensitive tissues. </span></strong><span style="color: rgb(44, 130, 201)"><strong>All steroids can cause androgenic side effects in direct relation to their affinity for this receptor, and </strong></span><span style="color: rgb(26, 188, 156)"><strong>DHT has no known unique ability in this regard"</strong></span></p><p></p><p>The main point to keep in mind regarding acne or hair loss (genetically prone individuals).....is that DHT is not the sole contributor and it is the general activation of the AR that is responsible.</p><p></p><p>As Nelson stated any AAS other than testosterone can result in acne in genetically prone individuals.</p></blockquote><p></p>
[QUOTE="madman, post: 172406, member: 13851"] Nelson replied: [URL='https://www.excelmale.com/forum/threads/nandrolone-added-to-trt-to-reduce-dht.20537/post-172311']Friday at 4:43 PM #23[/URL] [COLOR=rgb(184, 49, 47)][B]Nandrolone, even as monotherapy, can increase acne like any anabolic steroid used alone or with testosterone.[/B][/COLOR] Some men are prone to acne. Some do not get acne at all. Here are some good discussions on how to minimize sebum build up that can lead to acne: [URL='https://www.google.com/search?q=acne+excelmale.co+site:www.excelmale.com&sa=X&ved=2ahUKEwi8u-XU2-PnAhUD-6wKHRA0AnUQrQIoBDAAegQIBxAP&biw=1500&bih=809&dpr=2']Acne on testosterone and anabolic steroids[/URL] To add to that point: [B]William Llewellyn’s book: ANABOLICS[/B] [COLOR=rgb(184, 49, 47)]"As mentioned, testosterone also elicits [B]androgenic activity, which occurs by its activating receptors in what are considered to be androgen responsive tissues [/B](often through prior conversion to dihydrotestosterone. See DHT Conversion).[/COLOR] This includes the sebaceous glands, which are responsible for the secretion of oils in the skin. As the androgen level rises, so does the release of oils. As oil output increases, so does the chance for pores becoming clogged (we can see why acne is such a common side effect of steroid use). The production of body and facial hair is also linked to androgen receptor activation in skin and scalp tissues. This becomes most noticeable as boys mature into puberty, a period when testosterone levels rise rapidly, and androgen activity begins to stimulate the growth of hair on the body and face. [B][COLOR=rgb(44, 130, 201)]Some time later in life, and with the contribution of a genetic predisposition, androgen activity in the scalp may also help to initiate male-pattern hair loss.[/COLOR][/B] [COLOR=rgb(184, 49, 47)][B]It is a misconception that dihydrotestosterone is an isolated culprit in the promotion of hair loss, [/B][/COLOR][COLOR=rgb(44, 130, 201)][B]however; as in actuality it is the general activation of the androgen receptor that is to blame (see DHT Conversion).[/B] [/COLOR]The functioning of sex glands and libido are also tied to the activity of androgens, as are numerous other regions of the central nervous/neuromuscular system" [B]DHT and Androgenic Side Effects[/B] "In some regards, this local potentiation of testosterone's activity may be unwelcome, as higher androgenic activity in certain tissues may produce a number of undesirable side effects. [COLOR=rgb(184, 49, 47)][B]Acne, for example, is often triggered by dihydrotestosterone activity in the sebaceous glands, and the local formation of dihydrotestosterone in the scalp is typically blamed for triggering male pattern hair loss. [/B][/COLOR][COLOR=rgb(26, 188, 156)][B]You should know that it is a terrible misconception among bodybuilders that dihydrotestosterone is an isolated culprit when it comes to these side effects.[/B][/COLOR] [COLOR=rgb(44, 130, 201)][B]All anabolic/androgenic steroids exert their activities, both anabolic and androgenic, through the same cellular androgen receptor"[/B][/COLOR] [B][COLOR=rgb(184, 49, 47)]"Dihydrotestosterone is no different than any other steroid except that it is a more potent activator of this receptor than most, and can be formed locally in certain androgen-sensitive tissues. [/COLOR][/B][COLOR=rgb(44, 130, 201)][B]All steroids can cause androgenic side effects in direct relation to their affinity for this receptor, and [/B][/COLOR][COLOR=rgb(26, 188, 156)][B]DHT has no known unique ability in this regard"[/B][/COLOR] The main point to keep in mind regarding acne or hair loss (genetically prone individuals).....is that DHT is not the sole contributor and it is the general activation of the AR that is responsible. As Nelson stated any AAS other than testosterone can result in acne in genetically prone individuals. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Nandrolone added to TRT to reduce DHT?
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