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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Nandrolone added to TRT to reduce DHT?
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<blockquote data-quote="madman" data-source="post: 171799" data-attributes="member: 13851"><p>Great point as we have no idea where his DHT levels sit on such protocol.</p><p></p><p>Mind you I would me more interested in testing free DHT levels but even than what truly matters is (statements below).</p><p></p><p></p><p><strong>"Circulating levels of DHT in response to testosterone replacement therapy (TRT) do not correlate with those found in androgen sensitive tissue (e.g., prostate, adipose, muscle) <span style="color: rgb(184, 49, 47)">due to local regulatory mechanisms that tightly control intracellular androgen homeostasis"</span></strong></p><p></p><p><strong>"We are reminded of Horton’s admonition some 25 years ago when he concluded </strong></p><p><strong>that <span style="color: rgb(184, 49, 47)">blood levels of DHT provide only a hint of tissue levels</span> <span style="color: rgb(44, 130, 201)">and that DHT should be regarded as a paracrine hormone formed and acting primarily within target tissues (39)."</span></strong></p></blockquote><p></p>
[QUOTE="madman, post: 171799, member: 13851"] Great point as we have no idea where his DHT levels sit on such protocol. Mind you I would me more interested in testing free DHT levels but even than what truly matters is (statements below). [B]"Circulating levels of DHT in response to testosterone replacement therapy (TRT) do not correlate with those found in androgen sensitive tissue (e.g., prostate, adipose, muscle) [COLOR=rgb(184, 49, 47)]due to local regulatory mechanisms that tightly control intracellular androgen homeostasis"[/COLOR][/B] [B]"We are reminded of Horton’s admonition some 25 years ago when he concluded that [COLOR=rgb(184, 49, 47)]blood levels of DHT provide only a hint of tissue levels[/COLOR] [COLOR=rgb(44, 130, 201)]and that DHT should be regarded as a paracrine hormone formed and acting primarily within target tissues (39)."[/COLOR][/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Nandrolone added to TRT to reduce DHT?
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