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General Health & Fitness
Nutrition and Supplements
NAD, Hype Or Miracle Molecule?
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<blockquote data-quote="Will Brink" data-source="post: 144772" data-attributes="member: 2074"><p>I addressed that above and have read that study. I linked to a human study that found NR raised NAD+ levels in humans, and in addition to animal studies, we know not all orally ingested NR is converted the nicotinamide in the liver. That may also be why, per my article, infusions for those willing to that, + oral NR may be the optimal approach to keep NAD+ elevated, but we need more data on that one. I agree that it may be more beneficial to use methods that bypass first pass liver metabolism, but oral NR is still effective it appears.</p><p></p><p>Note also, that study is not oral NR vs NAD+ intravenous, but oral NR vs intravenous NR, so possible apples and oranges.</p></blockquote><p></p>
[QUOTE="Will Brink, post: 144772, member: 2074"] I addressed that above and have read that study. I linked to a human study that found NR raised NAD+ levels in humans, and in addition to animal studies, we know not all orally ingested NR is converted the nicotinamide in the liver. That may also be why, per my article, infusions for those willing to that, + oral NR may be the optimal approach to keep NAD+ elevated, but we need more data on that one. I agree that it may be more beneficial to use methods that bypass first pass liver metabolism, but oral NR is still effective it appears. Note also, that study is not oral NR vs NAD+ intravenous, but oral NR vs intravenous NR, so possible apples and oranges. [/QUOTE]
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General Health & Fitness
Nutrition and Supplements
NAD, Hype Or Miracle Molecule?
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