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General Health & Fitness
Nutrition and Supplements
NAD, Hype Or Miracle Molecule?
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<blockquote data-quote="Will Brink" data-source="post: 144738" data-attributes="member: 2074"><p>It's not a form of Niacin per se, but a downstream metabolite and if it consumed methyl groups to any great extent, the animal data, etc would not be so promising nor would low NAD+ levels be so strongly associated with so much negative age related stuff. No, that one is overly simplified. In some cases, for example creatine, you saves methyl groups as the production of creatine use more methyl groups than any reaction in the body. So, some times taking a metabolite, or the end product is a benefit, some times it's not...I have not looked at the full metabolic pathway for the production of NAD to see where methylation heavy reactions takes place, but I suspect it's not where as simple as your statement. If you can supply a source on that one via journals, I'll read it for sure.</p></blockquote><p></p>
[QUOTE="Will Brink, post: 144738, member: 2074"] It's not a form of Niacin per se, but a downstream metabolite and if it consumed methyl groups to any great extent, the animal data, etc would not be so promising nor would low NAD+ levels be so strongly associated with so much negative age related stuff. No, that one is overly simplified. In some cases, for example creatine, you saves methyl groups as the production of creatine use more methyl groups than any reaction in the body. So, some times taking a metabolite, or the end product is a benefit, some times it's not...I have not looked at the full metabolic pathway for the production of NAD to see where methylation heavy reactions takes place, but I suspect it's not where as simple as your statement. If you can supply a source on that one via journals, I'll read it for sure. [/QUOTE]
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General Health & Fitness
Nutrition and Supplements
NAD, Hype Or Miracle Molecule?
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