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General Health & Fitness
Nutrition and Supplements
NAC Benefits: HDL and More
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<blockquote data-quote="Jasen Bruce" data-source="post: 843" data-attributes="member: 14"><p><strong>N-acetyl cysteine (NAC)</strong> is an antioxidant that is used as a prescription drug and as a dietary supplement. As a drug, it is given orally to treat acetaminophen overdose. The inhalant and oral solution forms have a mucolytic effect to relieve obstructions in bronchial diseases and in tracheotomy procedures. The oral capsule is marketed as a dietary supplement for its liver protective function and is popular among patients with AIDS and cancer. Clinical studies show NAC can treat drug-induced hepatotoxicity, prevent and treat conditions of oxidative stress and reduced GSH levels caused by diseases such as HIV/AIDS and cancer, and alleviate toxicity from chemo- and radiotherapy. Results for treatment of chronic lung disease with NAC are mixed. NAC reduces the number of acute exacerbations in patients with chronic bronchopulmonary disease and significantly improves lung function and endurance in COPD patients after exercise, but these effects were not observed in other trials. NAC has no significant benefits in patients with cystic fibrosis or with Lou Gehrig's disease. NAC has glutamate modulating effect and has been tested as a treatment for psychiatric disorders including addictions and substance abuses. It also reduced symptoms of trichotillomania. Studies in smokers and patients with a history of adenomatous colonic polyps show NAC inhibits cancer biomarker development, although it did not inhibit the formation of secondary head and neck or lung tumors. One study suggests oral NAC can help reduce chemotherapy-induced neuropathy. NAC is generally safe, but gastrointestinal side effects have been reported. Due to its antioxidant activity, it may interfere with the actions of some chemotherapy drugs. ++</p></blockquote><p></p>
[QUOTE="Jasen Bruce, post: 843, member: 14"] [B]N-acetyl cysteine (NAC)[/B] is an antioxidant that is used as a prescription drug and as a dietary supplement. As a drug, it is given orally to treat acetaminophen overdose. The inhalant and oral solution forms have a mucolytic effect to relieve obstructions in bronchial diseases and in tracheotomy procedures. The oral capsule is marketed as a dietary supplement for its liver protective function and is popular among patients with AIDS and cancer. Clinical studies show NAC can treat drug-induced hepatotoxicity, prevent and treat conditions of oxidative stress and reduced GSH levels caused by diseases such as HIV/AIDS and cancer, and alleviate toxicity from chemo- and radiotherapy. Results for treatment of chronic lung disease with NAC are mixed. NAC reduces the number of acute exacerbations in patients with chronic bronchopulmonary disease and significantly improves lung function and endurance in COPD patients after exercise, but these effects were not observed in other trials. NAC has no significant benefits in patients with cystic fibrosis or with Lou Gehrig's disease. NAC has glutamate modulating effect and has been tested as a treatment for psychiatric disorders including addictions and substance abuses. It also reduced symptoms of trichotillomania. Studies in smokers and patients with a history of adenomatous colonic polyps show NAC inhibits cancer biomarker development, although it did not inhibit the formation of secondary head and neck or lung tumors. One study suggests oral NAC can help reduce chemotherapy-induced neuropathy. NAC is generally safe, but gastrointestinal side effects have been reported. Due to its antioxidant activity, it may interfere with the actions of some chemotherapy drugs. ++ [/QUOTE]
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General Health & Fitness
Nutrition and Supplements
NAC Benefits: HDL and More
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