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Nutrition and Supplements
NAC Benefits: HDL and More
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<blockquote data-quote="Nelson Vergel" data-source="post: 838" data-attributes="member: 3"><p>[ATTACH]211[/ATTACH]</p><p></p><p>NAC does not cause rash or flushing as Niacin. Men on high doses of testosterone have low HDL.</p><p></p><p>Pharmacol Res. 1993 Oct-Nov;28(3):213-8.</p><p><strong>Dose-related increase of HDL-cholesterol levels after N-acetylcysteine in man.</strong></p><p>Franceschini G, Werba JP, Safa O, Gikalov I, Sirtori CR.</p><p>Source</p><p>Centre E. Grossi Paoletti, University of Milano, Italy.</p><p>Abstract</p><p></p><p>Changes in plasma lipid-lipoprotein levels were evaluated in 10 hyperlipidemic patients during treatment with progressive doses (from 1200 mg day-1 to 3600 mg day-1) of N-acetylcysteine (NAC). Plasma total cholesterol and triglyceride levels, as well as those of lipoprotein (a) did not change to an appreciable extent, even with the highest dosage. However, the HDL-cholesterol levels showed a significant, dose-related rise, the mean absolute increase, with the highest NAC dose, being of approximately 10 mg dl-1 (16.2%). The rise of HDL-cholesterol was independent of changes in other lipid-lipoprotein parameters, suggesting a possible direct effect of NAC on the HDL system.</p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/n-acetylcysteine-a-review-of-clinical-usefulness.23724/#post-204625[/URL]</p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/the-mechanism-of-action-of-n-acetylcysteine-nac.24134/[/URL]</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 838, member: 3"] [ATTACH alt="nac.jpg"]211[/ATTACH] NAC does not cause rash or flushing as Niacin. Men on high doses of testosterone have low HDL. Pharmacol Res. 1993 Oct-Nov;28(3):213-8. [B]Dose-related increase of HDL-cholesterol levels after N-acetylcysteine in man.[/B] Franceschini G, Werba JP, Safa O, Gikalov I, Sirtori CR. Source Centre E. Grossi Paoletti, University of Milano, Italy. Abstract Changes in plasma lipid-lipoprotein levels were evaluated in 10 hyperlipidemic patients during treatment with progressive doses (from 1200 mg day-1 to 3600 mg day-1) of N-acetylcysteine (NAC). Plasma total cholesterol and triglyceride levels, as well as those of lipoprotein (a) did not change to an appreciable extent, even with the highest dosage. However, the HDL-cholesterol levels showed a significant, dose-related rise, the mean absolute increase, with the highest NAC dose, being of approximately 10 mg dl-1 (16.2%). The rise of HDL-cholesterol was independent of changes in other lipid-lipoprotein parameters, suggesting a possible direct effect of NAC on the HDL system. [URL unfurl="true"]https://www.excelmale.com/forum/threads/n-acetylcysteine-a-review-of-clinical-usefulness.23724/#post-204625[/URL] [URL unfurl="true"]https://www.excelmale.com/forum/threads/the-mechanism-of-action-of-n-acetylcysteine-nac.24134/[/URL] [/QUOTE]
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NAC Benefits: HDL and More
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