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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
My TRT Odyssey: Lab Results and More
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<blockquote data-quote="Cataceous" data-source="post: 276218" data-attributes="member: 38109"><p>Well nothing is completely trustworthy. I favor the Vermeulen calculation, but even an immunoassay-based TT test can be botched on occasion.</p><p></p><p>Your DHT didn't move, but estradiol nearly doubled. Even if some injection-site aromatization occurs, it seems pretty doubtful that estradiol production would be of that magnitude. The aromatase activity in those small volumes of tissue around a depot has to be pretty insignificant compared to total body activity. How can they alone make 60-100% of total body production? Higher local T concentrations don't help much because aromatase starts saturating at upper-end physiological levels.</p><p></p><p></p><p>Presumably not, since it refers specifically to enzyme inhibition. A quick search turns this up, though it's limited to one rat cell line:</p><p>[URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/7556776/[/URL]</p></blockquote><p></p>
[QUOTE="Cataceous, post: 276218, member: 38109"] Well nothing is completely trustworthy. I favor the Vermeulen calculation, but even an immunoassay-based TT test can be botched on occasion. Your DHT didn't move, but estradiol nearly doubled. Even if some injection-site aromatization occurs, it seems pretty doubtful that estradiol production would be of that magnitude. The aromatase activity in those small volumes of tissue around a depot has to be pretty insignificant compared to total body activity. How can they alone make 60-100% of total body production? Higher local T concentrations don't help much because aromatase starts saturating at upper-end physiological levels. Presumably not, since it refers specifically to enzyme inhibition. A quick search turns this up, though it's limited to one rat cell line: [URL unfurl="true"]https://pubmed.ncbi.nlm.nih.gov/7556776/[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
My TRT Odyssey: Lab Results and More
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