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I have been enjoying this informative thread, (kudos to Willyt for your detailed account), and decided to chime in with my alternate experience. I have been using an unesterified testosterone nasal mist for years that appears to have all of the benefits of Natesto (preservation of endogenous production through pulsing, ease of use, etc.) but with no goopy gel and for considerably less money. I am now in my mid-fifties and had tested for low/normal free testosterone levels about 5 years ago. The objective was to give myself a boost without shutting down my natural production.