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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My notes on Empower nasal T gel experiment
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<blockquote data-quote="Cataceous" data-source="post: 231816" data-attributes="member: 38109"><p>There are various negative feedback mechanisms in play in the hypothalamus to regulate testosterone production. The best known in these circles are the levels of free androgens and free estrogens. Among various other drivers is a starvation response. The starvation response is thought to lower hormones during periods of undernourishment so that energy is not expended on mating behavior. One hypothesized cause of secondary hypogonadism is a malfunction in the starvation response such that it is in effect even when calories are ample. This effectively makes the hypothalamus appear to be hypersensitive to the negative feedback of androgens and estrogens, resulting in a hormonal set point below what's normally considered healthy. Using exogenous testosterone to force serum testosterone above the lowered set point results in suppression unless the exogenous testosterone is very short-acting.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 231816, member: 38109"] There are various negative feedback mechanisms in play in the hypothalamus to regulate testosterone production. The best known in these circles are the levels of free androgens and free estrogens. Among various other drivers is a starvation response. The starvation response is thought to lower hormones during periods of undernourishment so that energy is not expended on mating behavior. One hypothesized cause of secondary hypogonadism is a malfunction in the starvation response such that it is in effect even when calories are ample. This effectively makes the hypothalamus appear to be hypersensitive to the negative feedback of androgens and estrogens, resulting in a hormonal set point below what's normally considered healthy. Using exogenous testosterone to force serum testosterone above the lowered set point results in suppression unless the exogenous testosterone is very short-acting. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
My notes on Empower nasal T gel experiment
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