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I have my doubts that TRT will ever work for me. I have identified my issues. Testosterone increases iron uptake by inhibiting hepcidin and regulates iron absorption.


When hepcidin is suppressed, more iron is available for the body to use.


This is precisely my problem. I experience high iron symptoms on TRT eating foods with iron in it, and unless I'm on the verge of an iron deficiency, this is the only time feel normal for a brief time after a blood donation, regardless of the TRT dosage.


I also can’t tolerate vitamin D supplementation on TRT. Vitamin D affects iron bioavailability, further exacerbating the issue. I have no problems while off TRT and supplementing vitamin D, as long as it’s kept under 2000 units otherwise I will get symptoms of excess iron.


Maybe a peptide can increase my natural T production. It's only been 5 days since stopping Jatenzo and last night my testicles started arching. My HPTA is strong at coming back online even after 7 years on TRT.


I want to get myself into a fasting state most of the day eating one meal per day in the evening but also working out every day.


Maybe a protein shake with peanut butter in the morning?


Can I do this without causing any harm?


TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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